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EVRI

Phase 1

Cancer | Small molecule | Oncology |Bristol-Myers Squibb Company|Trials Updated: Jul 31, 2008

EVRI target and mechanism

ModalitySmall molecule

Also known as EVRI (BMS-690514)

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment17

FDA Designations

No designations recorded

EVRI clinical trials

EVRI · 1 trial · 1 indication

Phase 1 1
NCT00578916Pharmacokinetics and Metabolism of Radiolabeled BMS-690514 in Healthy Male SubjectsCancer
COMPLETED17 Analytics
PHASE1COMPLETED
Pharmacokinetics and Metabolism of Radiolabeled BMS-690514 in Healthy Male Subjects
CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Single dose pharmacokinetics of BMS-690514 and radioactivity in plasma and urine
measured for 10 days post-dose

Secondary Endpoints

Determination of biotransformation profiles and recorded adverse events
for 10 days post-dose
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTAL -

Interventions

NameTypeDescription
EVRI (BMS-690514)DRUGOral Solution, Oral, 200 mg, single dose followed by 10-12 day inpatient stay
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Eligibility Criteria

Age Range18 Years to 45 Years
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy male subjects * Body mass index (BMS) of 18 - 30 kg/m², inclusive Exclusion Criteria: * Radiation exposure from diagnostic X-rays (except dental X-rays) in the last year or from clinical trials in the last 5 years

Countries:Switzerland
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Competitive Landscape -Cancer 7 trials

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Frequently asked questions about EVRI

What is EVRI?

EVRI is an investigational small molecule developed by Bristol-Myers Squibb for cancer. It is also known as BMS-690514. EVRI has been studied in a Phase 1 clinical trial and is not approved for any indication. The compound was evaluated in a pharmacokinetics and metabolism study in healthy male subjects.

What is EVRI used for?

EVRI is being developed for the treatment of cancer. It is an investigational agent and has not been approved for any use. The only clinical trial of EVRI listed was conducted in healthy male volunteers to study how the drug is processed in the body, not to treat patients.

Who makes EVRI?

EVRI is made by Bristol-Myers Squibb Company, which trades on the New York Stock Exchange under the ticker BMY. Bristol-Myers Squibb is the developer of EVRI, also known as BMS-690514.

What phase is EVRI in?

EVRI is in Phase 1 clinical development. It is an investigational drug and has not been approved by the FDA or any other regulatory agency. The Phase 1 program for EVRI has been completed.

What clinical trials is EVRI in?

EVRI has been studied in one clinical trial, NCT00578916, titled Pharmacokinetics and Metabolism of Radiolabeled BMS-690514 in Healthy Male Subjects. The trial was a completed Phase 1 study that enrolled 17 healthy male volunteers in Switzerland. No active trials of EVRI are ongoing.

Is EVRI the same as BMS-690514?

Yes, EVRI is also known as BMS-690514. Bristol-Myers Squibb developed the compound under the designation BMS-690514, and EVRI is an alternative name for the same investigational small molecule being studied in cancer.