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CC-90006

Phase 1

Healthy Volunteers | Small molecule | Other |Bristol-Myers Squibb Company|Last Updated: May 7, 2020

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment40

FDA Designations

No designations recorded

Clinical trial landscape

CC-90006 · 2 trials · 2 indications

Phase 1 2
NCT03337022Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of CC-90006 in Subjects With Mild to Moderate Plaque-type PsoriasisPsoriasis
COMPLETED34 Analytics
NCT02934269A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CC-90006 in Healthy SubjectsHealthy Volunteers
COMPLETED40 Analytics
PHASE1COMPLETED
Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of CC-90006 in Subjects With Mild to Moderate Plaque-type Psoriasis
PsoriasisUnlock trial analytics
PHASE1COMPLETED
A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CC-90006 in Healthy Subjects
Healthy VolunteersUnlock trial analytics

Study Endpoints

Primary Endpoints

Adverse Events (AEs)
Up to approximately Week 20

Number of participants with adverse events

Secondary Endpoints

Pharmacokinetics: Cmax
Up to approximately 16 weeks
Pharmacokinetics - Tmax
Up to approximately 16 weeks
Pharmacokinetics - AUC 0-t
Up to approximately 16 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
CC-90006; Dose level 1EXPERIMENTALCC-90006 will be administered subcutaneously (SC) on days 1, 15, and 29.
CC-90006; Dose level 2EXPERIMENTALCC-90006 will be administered subcutaneously (SC) on days 1, 15, and 29.
CC-90006; Dose level 3EXPERIMENTALCC-90006 will be administered subcutaneously (SC) on days 1, 15, and 29.
CC-90006; Dose level 4EXPERIMENTALCC-90006 will be administered subcutaneously (SC) on days 1, 15, and 29.
PlaceboPLACEBO_COMPARATORPlacebo (saline) will be administered subcutaneously (SC) on days 1, 15, and 29.
CC-90006; Dose Level 5EXPERIMENTALCC-90006 will be administered by subcutaneous injection in the abdomen

Interventions

NameTypeDescription
CC-90006DRUGCC-90006
PlaceboOTHERPlacebo
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Eligibility Criteria

Age Range18 Years to 60 Years
SexALL
Healthy VolunteersNo
Study Sites4

Inclusion Criteria: The following is a summary of the inclusion criteria: 1. Males or non-pregnant females between the ages of 18 and 60 years (inclusive) at the time of signing the ICF, and be willing to adhere to the requirements of contraception use throughout the study. 1. Female subjects ...

Countries:United StatesCanada
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Frequently asked questions about CC-90006

What is CC-90006 used for?

CC-90006 is an investigational small molecule being studied for use in healthy volunteers and in patients with mild to moderate plaque-type psoriasis. It is currently in Phase 1 clinical development and is not approved by the FDA.

Who makes CC-90006?

CC-90006 is being developed by Bristol-Myers Squibb Company, which trades under the ticker symbol BMY on the New York Stock Exchange.

What phase is CC-90006 in?

CC-90006 is in Phase 1 clinical development. Two Phase 1 trials have been completed, one in healthy volunteers and one in patients with mild to moderate plaque-type psoriasis. The drug is investigational and has not been approved.

What clinical trials is CC-90006 in?

CC-90006 has been studied in two completed Phase 1 trials. NCT02934269 evaluated safety, tolerability, pharmacokinetics, and pharmacodynamics in 40 healthy subjects in the United States. NCT03337022 evaluated safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity in 34 subjects with mild to moderate plaque-type psoriasis in the United States and Canada.

Is CC-90006 the same as any other drug?

No alternative names for CC-90006 have been disclosed. It is identified solely by its code name CC-90006 in clinical trial registries and by its developer, Bristol-Myers Squibb.