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CC-90006

Phase 1

Psoriasis | Small molecule | Dermatology |Bristol-Myers Squibb Company|Trials Updated: May 7, 2020

CC-90006 development status

Highest phase Phase 1
Registered trials 2 across 1 sponsor since Oct 2016

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment34

FDA Designations

No designations recorded

CC-90006 clinical trials

CC-90006 · 1 trial · 1 indication

Phase 1 1
NCT03337022Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of CC-90006 in Subjects With Mild to Moderate Plaque-type PsoriasisPsoriasis
COMPLETED34 Analytics
PHASE1COMPLETED
Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of CC-90006 in Subjects With Mild to Moderate Plaque-type Psoriasis
PsoriasisUnlock trial analytics

Study Endpoints

Primary Endpoints

Adverse Events (AEs)
Up to approximately Week 20

Number of participants with adverse events

Secondary Endpoints

Pharmacokinetics: Cmax
Up to approximately 16 weeks
Pharmacokinetics - Tmax
Up to approximately 16 weeks
Pharmacokinetics - AUC 0-t
Up to approximately 16 weeks
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
CC-90006; Dose level 1EXPERIMENTALCC-90006 will be administered subcutaneously (SC) on days 1, 15, and 29.
CC-90006; Dose level 2EXPERIMENTALCC-90006 will be administered subcutaneously (SC) on days 1, 15, and 29.
CC-90006; Dose level 3EXPERIMENTALCC-90006 will be administered subcutaneously (SC) on days 1, 15, and 29.
CC-90006; Dose level 4EXPERIMENTALCC-90006 will be administered subcutaneously (SC) on days 1, 15, and 29.
PlaceboPLACEBO_COMPARATORPlacebo (saline) will be administered subcutaneously (SC) on days 1, 15, and 29.

Interventions

NameTypeDescription
CC-90006DRUGCC-90006
PlaceboOTHERPlacebo
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Eligibility Criteria

Age Range18 Years to 60 Years
SexALL
Healthy VolunteersNo
Study Sites4

Inclusion Criteria: The following is a summary of the inclusion criteria: 1. Males or non-pregnant females between the ages of 18 and 60 years (inclusive) at the time of signing the ICF, and be willing to adhere to the requirements of contraception use throughout the study. 1. Female subjects ...

Countries:United StatesCanada
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Frequently asked questions about CC-90006

What is CC-90006?

CC-90006 is an investigational small molecule developed by Bristol-Myers Squibb Company (ticker: BMY) for the treatment of psoriasis, a dermatological condition. It has been studied in a Phase 1 clinical trial in adults with mild to moderate plaque-type psoriasis. It is not an approved therapy and remains in clinical development.

What is CC-90006 used for in psoriasis?

CC-90006 was studied for the treatment of mild to moderate plaque-type psoriasis in adults aged 18 years and older. The single Phase 1 trial enrolled 34 participants with this condition in the United States and Canada. Because the program is at the Phase 1 stage, CC-90006 is investigational and has no approved use.

Who makes CC-90006?

CC-90006 is developed by Bristol-Myers Squibb Company, which trades under the ticker BMY. The company sponsored the Phase 1 study of the compound in patients with mild to moderate plaque-type psoriasis. Bristol-Myers Squibb is the developer associated with this asset.

What phase is CC-90006 in?

CC-90006 is in Phase 1 clinical development. One Phase 1 trial has been completed, and no trials are currently active. The study was randomized, double-blind, and placebo-controlled, enrolling 34 participants. CC-90006 is investigational and has not been approved for any indication.

What clinical trials is CC-90006 in?

CC-90006 has been evaluated in one clinical trial, NCT03337022, titled a study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity of CC-90006 in subjects with mild to moderate plaque-type psoriasis. The Phase 1 trial is completed, enrolled 34 participants, and was conducted in the United States and Canada.

Was the CC-90006 trial placebo-controlled?

Yes. The Phase 1 trial of CC-90006, NCT03337022, was randomized, double-blind, and placebo-controlled. It enrolled 34 adults with mild to moderate plaque-type psoriasis across sites in the United States and Canada. The study assessed safety, tolerability, pharmacokinetics, pharmacodynamics, and immunogenicity, and it is now completed.