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BMS-986120

Phase 1

Thrombosis | Small molecule | Cardiovascular |Bristol-Myers Squibb Company|Trials Updated: Sep 8, 2016

BMS-986120 development status

Highest phase Phase 1
Registered trials 2 across 1 sponsor since Aug 2014

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment42

FDA Designations

No designations recorded

BMS-986120 clinical trials

BMS-986120 · 1 trial · 1 indication

Phase 1 1
NCT02439190CV004-007 Thrombosis Chamber StudyThrombosis
COMPLETED42 Analytics
PHASE1COMPLETED
CV004-007 Thrombosis Chamber Study
ThrombosisUnlock trial analytics

Study Endpoints

Primary Endpoints

Change from baseline in thrombus area (post-treatment with BMS-986120 vs. pre-treatment)
2 days

Secondary Endpoints

Safety and tolerability of BMS 986120 or aspirin administered with and without clopidogrel based on adverse events,clinical laboratory tests, physical examinations and vital signs per the collection schedule
2 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL

Treatment Arms

ArmTypeDescription
Treatment A: BMS-986120ACTIVE_COMPARATORBMS-986120 on specified days
Treatment B: Aspirin and ClopidogrelACTIVE_COMPARATORAspirin and Clopidogrel on specified days

Interventions

NameTypeDescription
BMS-986120DRUG -
AspirinDRUG -
ClopidogrelDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites1

For more information regarding BMS clinical trial participation, please visit www.BMSStudyConnect.com Inclusion Criteria: * Healthy subjects as determined by no clinically significant deviation from normal in medical history, physical examination, ECGs and clinical laboratory determinations * Body...

Countries:United Kingdom
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Competitive Landscape -Thrombosis and Embolism 38 trials (matched to "Thrombosis")

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Frequently asked questions about BMS-986120

What is BMS-986120 used for?

BMS-986120 is an investigational small molecule being studied for thrombosis, the formation of blood clots inside blood vessels. It is in Phase 1 clinical development for this cardiovascular indication. It has not been approved for any use, and its only recorded human study has been completed.

Who is developing BMS-986120?

BMS-986120 is being developed by Bristol-Myers Squibb Company, which trades on the New York Stock Exchange under the ticker BMY. The company sponsored the Phase 1 thrombosis chamber study of the compound conducted in the United Kingdom.

What phase is BMS-986120 in?

BMS-986120 is in Phase 1 clinical development. One Phase 1 trial has been completed, and no trials are currently active. The program remains investigational, and BMS-986120 has not been approved by the FDA or any other regulatory authority for commercial use.

What clinical trials is BMS-986120 in?

BMS-986120 has been evaluated in one completed Phase 1 study, NCT02439190, titled CV004-007 Thrombosis Chamber Study. It enrolled 42 participants aged 18 years and older in the United Kingdom, used an active-controlled randomized design, and included healthy volunteers.

What does BMS-986120 target?

BMS-986120 is a small molecule developed for thrombosis. It was studied in a Phase 1 thrombosis chamber model that assessed clot formation in healthy volunteers under active-controlled, randomized conditions, with 42 participants enrolled in the completed trial.