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BMS-791826

Phase 1

Immunoscience | Small molecule | Immunology |Bristol-Myers Squibb Company|Last Updated: Jun 9, 2020

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLEDDMC
Total Trials1
Total Enrollment120

FDA Designations

No designations recorded

Clinical trial landscape

BMS-791826 · 1 trial · 1 indication

Phase 1 1
NCT03198013A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy MalesImmunoscience
COMPLETED120 Analytics
PHASE1COMPLETED
A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males
ImmunoscienceUnlock trial analytics

Study Endpoints

Primary Endpoints

Incidence of Adverse Events (AEs)
Up to 34 days

safety and tolerability

Incidence of serious adverse events (SAEs)
Up to 34 days

safety and tolerability

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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeBASIC_SCIENCE

Treatment Arms

ArmTypeDescription
Module AEXPERIMENTALSingle Ascending Dose
Module BEXPERIMENTALMultiple Ascending Dose

Interventions

NameTypeDescription
PrednisoloneDRUGSpecified dose on specified days
BMS-791826DRUGSpecified dose on specified days
PlaceboDRUGSpecified dose on specified days
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Eligibility Criteria

Age Range18 Years to 55 Years
SexMALE
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Healthy male subjects as determined by no clinically significant deviation from normal in medical history, physical examination, electrocardiograms (ECGs), and clinical laboratory determinations * Body Mass Index (BMI) of 18 to 30 kilogram / square meter (kg/m2), inclusive * S...

Countries:Australia
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Frequently asked questions about BMS-791826

What is BMS-791826?

BMS-791826 is an investigational small molecule being developed by Bristol-Myers Squibb for use in immunoscience, a therapeutic area focused on immunology. It is currently in Phase 1 clinical development. The drug has been studied in a clinical trial involving healthy male participants.

What does BMS-791826 target?

The specific molecular target of BMS-791826 has not been disclosed. It is being developed as a small molecule for immunoscience indications, which typically involve modulating immune system pathways, but the exact target is not publicly available.

Who makes BMS-791826?

BMS-791826 is being developed by Bristol-Myers Squibb Company, a global biopharmaceutical company. The company's stock is traded under the ticker symbol BMY on the New York Stock Exchange.

What phase is BMS-791826 in?

BMS-791826 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The drug is being studied for its pharmacokinetics and pharmacodynamics in healthy volunteers.

What clinical trials is BMS-791826 in?

BMS-791826 has been studied in one completed Phase 1 clinical trial with the identifier NCT03198013. This trial, titled 'A Study of Pharmacokinetics (PK) and Pharmacodynamics (PD) in Relation to Prednisolone in Healthy Males,' enrolled 120 healthy male participants in Australia.

Is BMS-791826 the same as prednisolone?

No, BMS-791826 is not the same as prednisolone. Prednisolone is a corticosteroid used as a reference drug in the clinical trial to study the pharmacokinetics and pharmacodynamics of BMS-791826. BMS-791826 is a separate investigational small molecule being developed by Bristol-Myers Squibb.