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BMS-770767

Phase 2

Diabetes Type 2 | Small molecule | Metabolic |Bristol-Myers Squibb Company|Last Updated: Oct 12, 2015

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment76

FDA Designations

No designations recorded

Clinical trial landscape

BMS-770767 · 2 trials · 2 indications

Phase 2 2
NCT01046422Safety Study of BMS-770767 in Subjects With Type 2 DiabetesDiabetes Type 2
COMPLETED76 Analytics
NCT01058083Safety Study of BMS-770767 in Subjects With HypercholesterolemiaDyslipidemia
COMPLETED81 Analytics
PHASE2COMPLETED
Safety Study of BMS-770767 in Subjects With Type 2 Diabetes
Diabetes Type 2Unlock trial analytics
PHASE2COMPLETED
Safety Study of BMS-770767 in Subjects With Hypercholesterolemia
DyslipidemiaUnlock trial analytics

Study Endpoints

Primary Endpoints

Fasting Plasma Glucose Improvement
Within seven days following dosing
Lowering of LDL-C
Within 28 days following dosing

Secondary Endpoints

Mean daily glucose (3-day 7 pt-fingerstick)
Within 28 days following dosing
Four (4)-hour post-prandial glucose AUC
Within 28 days following dosing
HbA1C
Within 28 days following dosing
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Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
BMS-770767 ± metformin (Treatment A)EXPERIMENTAL -
BMS-770767 ± metformin (Treatment B)EXPERIMENTAL -
BMS-770767 ± metformin (Treatment C)EXPERIMENTAL -
BMS-770767 ± metformin (Treatment D)EXPERIMENTAL -
Placebo ± metformin (Treatment E)PLACEBO_COMPARATOR -
BMS-770767 (Treatment A)EXPERIMENTAL -
BMS-770767 (Treatment B)EXPERIMENTAL -
BMS-770767 (Treatment C)EXPERIMENTAL -
BMS-770767 (Treatment D)EXPERIMENTAL -
Placebo (Treatment E)PLACEBO_COMPARATOR -

Interventions

NameTypeDescription
BMS-770767DRUGCapsule, Oral, 15mg, Active, Daily, 28 days
PlaceboDRUGCapsule, Oral, 0mg, Daily, 28 days
MetforminDRUGTablet, Oral, ≥ 1500mg, Active, Daily, 28 days
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Eligibility Criteria

Age Range18 Years to 75 Years
SexALL
Healthy VolunteersNo
Study Sites18

Inclusion Criteria: * Diagnosed with type 2 diabetes with inadequate glycemic control and treated with either diet and exercise alone, or with stable doses (≥ 1500mg/d) of metformin for at least 8 weeks prior to screening * HbA1c ≥ 7.0% and ≤ 10.0% with FPG ≤ 240mg/dL (13.3 mmol/dL) Exclusion Crit...

Countries:United StatesAustraliaCanadaSouth Korea
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Competitive Landscape -Diabetes Complications 6 trials (matched to "Diabetes Type 2")

Frequently asked questions about BMS-770767

What is BMS-770767 used for?

BMS-770767 is an investigational small molecule being developed by Bristol-Myers Squibb for the treatment of Type 2 diabetes and dyslipidemia. It has been studied in Phase 2 clinical trials for these metabolic conditions, though it is not yet approved and remains in clinical development.

Who makes BMS-770767?

BMS-770767 is being developed by Bristol-Myers Squibb Company, which trades under the ticker BMY. The company has conducted Phase 2 clinical trials to evaluate the drug's safety in patients with Type 2 diabetes and dyslipidemia.

What phase is BMS-770767 in?

BMS-770767 is in Phase 2 clinical development. It has completed two Phase 2 trials, one in Type 2 diabetes and one in dyslipidemia. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is BMS-770767 in?

BMS-770767 has been studied in two completed Phase 2 trials. NCT01046422 evaluated the drug in 76 participants with Type 2 diabetes, while NCT01058083 enrolled 81 participants with hypercholesterolemia, a form of dyslipidemia. Both trials were randomized, double-blind, and placebo-controlled.

Is BMS-770767 the same as any other drug?

No alternative names for BMS-770767 have been disclosed. The drug is identified solely by its development code and is being studied under the clinical trial identifiers NCT01046422 and NCT01058083.