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Admilparant

Phase 1

Healthy Participants | Small molecule | Other |Bristol-Myers Squibb Company|Last Updated: Jan 14, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedCONTROLLED
Total Trials1
Total Enrollment56
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT07225647A Study to Assess the Effect of Food on the Drug Levels of AdmilparantPHASE1 COMPLETED 56 — — Nov 7, 2025Jan 5, 2026Jan 14, 20262 United States
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Study Endpoints
Primary Endpoints
Maximum observed plasma concentration (Cmax)
Up to 13 days
Area under the concentration-time curve from time zero to time of last quantifiable concentration (AUC(0-T))
Up to 13 days
Area under the concentration-time curve from time zero extrapolated to infinite time (AUC(INF))
Up to 13 days
Secondary Endpoints
Time of maximum observed plasma concentration (Tmax)
Up to 13 days
Terminal half-life (T-HALF)
Up to 13 days
Apparent total body clearance (CLT/F)
Up to 13 days
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Part 1: Treatment AEXPERIMENTAL -
Part 1: Treatment BEXPERIMENTAL -
Part 2: Treatment CEXPERIMENTAL -
Part 2: Treatment DEXPERIMENTAL -
Interventions
NameTypeDescription
AdmilparantDRUGSpecified dose on specified days
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Eligibility Criteria
Age Range18 Years — 65 Years
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria * Participants must have a body mass index (BMI) of 18.0 kg/m2 to 32.0 kg/m2, inclusive, at screening. * Participants must have a body weight of ≥ 50 kg for males and ≥ 45 kg for females at screening. Exclusion Criteria * Participants must not have any significant medical condi...

Countries:United States
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