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BlossomHill Therapeutics, Inc. Common Stock

BLSMFDA catalysts, PDUFA dates & pipeline intelligence
$15.6
▲ +1.2 · +8.33%

Financials

Last updated
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R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
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Quarterly Cash
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Volume
76.27 K
Value Traded
6.71 M
Short % Float
2.1%
Days to Cover
1.6
+4.14%Week
-38.22%1 Month
-2.5%3 Month
-2.5%6 Month

Cash Data

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  • Burn Trend
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  • SEC Filing

Key Stats

Market Cap
495.84 M
EPS (TTM)
-
P/E Ratio
-
Ent. Value
400.47 M
Total Shares
31.78 M
Float Shares
22.59 M
Insiders
28.93%
Institutions
20.63%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
IND Submission
BH-501284
diverse KRAS-mutant tumors
INDSmall MoleculesOncology
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

BLSM Catalyst Timeline

Dated clinical, regulatory and corporate events for BlossomHill Therapeutics, Inc. Common Stock

Catalyst Timeline

Dated clinical, regulatory & corporate events for BlossomHill Therapeutics, Inc. Common Stock

26Total events
10Upcoming
1Tier-1 (high impact)
2026 to 2028Coverage

Upcoming catalysts 2

T3End Of Phase 1 Meeting
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BH-30643
T2Timing Guidance
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BH-30643

Event history 12

▲Preclinical PoCBH-501284Preclinical
Preclinical data for BH-501284 presented at AACR Conference on Pancreatic Cancer
KRAS-mutant cancers (pancreatic, lung, colorectal)source ↗
●Quarterly UpdateCorporate
BlossomHill Therapeutics reports second quarter 2026 financial results
▲Oral PresentationBH-30643Presentation
Updated Phase 1/2 SOLARA data presented in mini-oral presentation at IASLC 2026 World Conference on Lung Cancer
EGFR C797S-positive NSCLCsource ↗
▲Fast Track DesignationBH-30643Designation
FDA granted Fast Track designation to BH-30643
advanced or metastatic EGFR C797S-positive non-small cell lung cancer (NSCLC) after prior treatment with a third-generation EGFR TKIsource ↗
▼Equity OfferingCorporate
Completion of upsized $168.3 million initial public offering
●Oral PresentationBH-30643Presentation
Preliminary BH-30643 Phase 1 dose escalation data presented at ASCO 2026
EGFR-mutant NSCLCsource ↗
●Oral PresentationBH-30236Presentation
Initial BH-30236 Phase 1/1b clinical data presented at EHA 2026 Congress
R/R AML and HR-MDSsource ↗
▲Additional DataBH-30643Clinical Data
Updated SOLARA data: 45% ORR and 88% DCR in EGFR C797S-positive NSCLC
EGFR C797S-positive NSCLCsource ↗
▲Safety Data UpdateBH-30643Clinical Data
Favorable safety profile reported at 40/50/60 mg BID expansion doses
EGFR-mutant NSCLCsource ↗
●Preclinical PoCBH-501284Preclinical
First preclinical data for pan-KRAS inhibitor BH-501284 presented at AACR 2026
KRAS-mutant tumorssource ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How BLSM actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-09-15BH-30643 Phase 1/2 data presentation Phase 1/2
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

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Every scored asset with PTRS, rNPV, enrollment velocity and trial design quality.
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Clinical Trial Results

Readouts, endpoints and source filings for every BLSM program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
BH-30643
Fast Track
EGFR C797S-positive NSCLCPhase 1/22026-09-15objective response rate: 45%; disease control rate: 88%; patients on treatment: 63%; median follow up: 6.9 monthsRead MoreBlossomHill Therapeutics Presents Updated Data from Ongoing Phase 1/2 SOLARA Trial Demonstrating Encouraging Anti-Tumor Activity of OMNI-EGFR™ Inhibitor BH-30643 in EGFR C797S-Positive NSCLC at IASLC 2026 World Conference on Lung CancerRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Chen BihuaDirector, 10% OwnerBuy 312,500 3,614,034 held$16.00 08/10/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
No hedge fund reported a 13F position in BLSM for Q2 2026.
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

BLSM Institutional Ownership Trends

BLSM Short Interest

Shares sold short, counted twice a month.

2.1%
Short % of Float
of tradable shares sold short
473.8K
Shares Sold Short
+244.4% vs prior count
1.6 Low
Days to Cover
trading days of normal volume to buy every short share back
291.7K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How BLSM ranks across every disease it competes in

Competitive Position is a premium feature
See how BLSM ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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BLSM News

-BLSM
Oct 22, 2026
BLSMPhases
▲ +8.3%today

BlossomHill Therapeutics Announces Collaboration with Foundation Medicine to Develop First Companion Diagnostic for BH-30643 in EGFR C797S Mutated Non-Small Cell Lung Cancer

BlossomHill Therapeutics announced a collaboration with Foundation Medicine to develop a companion diagnostic assay for the EGFR C797S mutation in non-small cell lung cancer. This partnership will support the ongoing Phase 1/2 SOLARA trial of BH-30643, a novel treatment targeting this resistance mutation. The collaboration aims to validate the diagnostic assay to guide BH-30643's development.

Read more →
-BLSM
Sep 28, 2026
BLSMPhases
▲ +8.1%on this news

BlossomHill Therapeutics Presents Preclinical Data on Novel Pan-KRAS Inhibitor, BH-501284, at the AACR Conference on Pancreatic Cancer

BlossomHill Therapeutics presented promising preclinical data on BH-501284, a novel pan-KRAS inhibitor, at the AACR Conference. The data indicate that BH-501284 achieves prolonged target engagement and significant antitumor activity in various KRAS-mutant cancer models. The company aims for an IND submission in Q1 2027, highlighting the potential of this innovative therapy.

Read more →
-BLSM
Sep 18, 2026
BLSMFDA Updates

BlossomHill Therapeutics Reports Second Quarter 2026 Financial Results

BlossomHill Therapeutics reported strong financial results for Q2 2026, highlighted by a successful IPO that raised $168.3 million. The company announced FDA Fast Track designation for its drug BH-30643, aimed at treating advanced EGFR C797S-positive NSCLC. Preliminary trial results show promising efficacy, and the company is preparing for key upcoming milestones in its clinical development pipeline.

Read more →
-BLSM
Sep 15, 2026
BLSMPhases

BlossomHill Therapeutics Presents Updated Data from Ongoing Phase 1/2 SOLARA Trial Demonstrating Encouraging Anti-Tumor Activity of OMNI-EGFR™ Inhibitor BH-30643 in EGFR C797S-Positive NSCLC at IASLC 2026 World Conference on Lung Cancer

BlossomHill Therapeutics presented updated data from the Phase 1/2 SOLARA trial, highlighting the efficacy of BH-30643 in treating EGFR C797S-positive NSCLC. The trial reported a 45% objective response rate and an 88% disease control rate among patients resistant to prior EGFR inhibitors. BH-30643 also demonstrated a favorable safety profile, with minimal treatment-related adverse events. The company plans to advance to a Phase 2 trial in 2027 following FDA Fast Track designation.

Read more →
-BLSM
Sep 3, 2026
BLSMConferences/Events

BlossomHill Therapeutics to Present at the 8th Annual RAS-Targeted Drug Development Summit & H.C. Wainwright 28th Annual Global Investment Conference

BlossomHill Therapeutics, a clinical-stage biopharmaceutical company, announced its participation in two significant conferences: the 8th Annual RAS-Targeted Drug Development Summit and the H.C. Wainwright 28th Annual Global Investment Conference. Key presentations will be made by Dr. Geoff Oxnard and Dr. Jean Cui. The company aims to showcase its innovative cancer treatments and engage with investors.

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-BLSM
Sep 1, 2026
BLSMPhases

BlossomHill Therapeutics to Present Updated Data from Ongoing Phase 1/2 SOLARA Trial of its Macrocyclic OMNI-EGFR™ Inhibitor, BH-30643, in EGFR-mutant NSCLC at the 2026 World Conference on Lung Cancer

BlossomHill Therapeutics will present updated data from the Phase 1/2 SOLARA trial for BH-30643, an investigational treatment for EGFR-mutant NSCLC, at the 2026 World Conference on Lung Cancer. The data will focus on the drug's anti-tumor activity against secondary EGFR resistance mutations, particularly C797S. This presentation is significant as there are currently no approved therapies for patients with this mutation.

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-BLSM
Aug 18, 2026
BLSMFDA Updates

BlossomHill Therapeutics Announces FDA Fast Track Designation for BH-30643, a Macrocyclic OMNI-EGFR™ Inhibitor for the Treatment of Advanced EGFR C797S-positive NSCLC

BlossomHill Therapeutics has received FDA Fast Track designation for its investigational drug BH-30643, aimed at treating advanced EGFR C797S-positive non-small cell lung cancer. This designation acknowledges the drug's potential to meet significant unmet medical needs. BH-30643 is currently being evaluated in a global Phase 1/2 clinical trial, SOLARA, across multiple sites. The Fast Track status may allow for more frequent interactions with the FDA and eligibility for accelerated approval.

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-BLSM
Aug 7, 2026
BLSMGeneral

BlossomHill Therapeutics Announces Pricing of Upsized $150 Million Initial Public Offering

BlossomHill Therapeutics has announced the pricing of its upsized initial public offering, offering 9,375,000 shares at $16.00 each, aiming to raise $150 million. The shares will begin trading on Nasdaq under the ticker 'BLSM' on August 7, 2026. The offering is set to close on August 10, 2026, pending customary conditions.

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-BLSM
Jun 11, 2026
BLSMPhases

BlossomHill Therapeutics Presents Initial Clinical Data from Dose Escalation in Ongoing Phase 1/1b Trial of Novel Macrocyclic CLK Inhibitor, BH-30236, in Patients with R/R AML or HR-MDS at EHA 2026

BlossomHill Therapeutics presented initial clinical data on BH-30236, a novel CLK inhibitor, at the EHA 2026 Congress. The drug showed promising anti-leukemic activity in patients with relapsed or refractory AML and higher-risk MDS, particularly in those resistant to prior venetoclax therapy. The trial results indicate a favorable safety profile and potential for further development.

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-BLSM
May 21, 2026
BLSMPhases

BlossomHill Therapeutics to Present Preliminary Results From Phase 1 Dose Escalation/Backfill Cohorts in Phase 1/2 SOLARA Trial of OMNI-EGFR Inhibitor, BH-30643, in Advanced EGFR-mutant NSCLC at the 2026 ASCO Annual Meeting

BlossomHill Therapeutics is set to present preliminary results from the Phase 1 dose escalation/backfill cohorts of the SOLARA trial for BH-30643, an OMNI-EGFR inhibitor, at the 2026 ASCO Annual Meeting. The data indicate promising clinical activity in advanced EGFR-mutant NSCLC, particularly in patients with challenging mutations. The ongoing Phase 1 dose expansion aims to determine the recommended Phase 2 dose.

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-BLSM
May 20, 2026
BLSMGeneral

BlossomHill Therapeutics Expands Board of Directors with the Appointments of Sheila Gujrathi, M.D., and John Schmid

BlossomHill Therapeutics has expanded its Board of Directors with the appointments of Dr. Sheila Gujrathi and John Schmid. Both appointees bring extensive experience in biopharmaceuticals, which is expected to support the company's growth in developing next-generation cancer medicines. The company is advancing multiple precision oncology programs and aims to improve patient outcomes.

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About BlossomHill Therapeutics, Inc. Common Stock

San Diego, CA 69 employees bhtherapeutics.com
Headquarters10255 SCIENCE CENTER DRIVE, SAN DIEGO, CA
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