Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00905762 | Concentration of Besifloxacin, Gatifloxacin, and Moxifloxacin in Human Conjunctiva After Topical Instillation | PHASE1 | COMPLETED | 119 | — | — | Mar 1, 2009 | Apr 1, 2009 | Dec 9, 2011 | 1 | United States |
| Arm | Type | Description |
|---|---|---|
| Besifloxacin | EXPERIMENTAL | Besifloxacin one drop instilled into study eye. |
| Gatifloxacin | ACTIVE_COMPARATOR | Gatifloxacin one drop instilled into study eye. |
| Moxifloxacin | ACTIVE_COMPARATOR | Moxifloxacin one drop instilled into study eye. |
| Name | Type | Description |
|---|---|---|
| Gatifloxacin | DRUG | Gatifloxacin 0.3% one drop instilled into study eye at visit 2. |
| Moxifloxacin | DRUG | Moxifloxacin 0.5% one drop instilled into study eye at visit 2. |
| Besifloxacin | DRUG | Besifloxacin 0.6% one drop instilled into study eye at visit 2. |
Inclusion Criteria: * Willing to avoid all disallowed medications for the appropriate washout periods. * Have a best corrected visual acuity of 0.60 logMAR or better in each eye as measured using an ETDRS chart. Exclusion Criteria: * Have a known allergy and/or sensitivity to the test articles or...