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Ifosfamide

Phase 2

Non-Hodgkins Lymphoma | Small molecule | Oncology |Biogen Inc.|Last Updated: May 3, 2011

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment40
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00193505Ifosfamide/Carboplatin/Etoposide/Rituxan Followed by Zevalin in Relapsed/Refractory Intermediate Grade B-Cell LymphomaPHASE2 COMPLETED 40Oct 1, 2003Aug 1, 2005May 3, 20111 United States
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Study Endpoints
Primary Endpoints
complete response rate
Secondary Endpoints
progression-free survival
overall survival
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Study Design & Arms
AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Interventions
NameTypeDescription
IfosfamideDRUG -
CarboplatinDRUG -
EtoposideDRUG -
RituximabDRUG -
90Y ZevalinDRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: To be included in this study, you must meet the following criteria: * Intermediate grade CD20-positive B-cell non-Hodgkin's lymphoma * Persistent lymphoma after one or two previous chemotherapy regimens * Patients should not be considered candidates for high-dose chemotherapy *...

Countries:United States
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