Recent Updates
Recently added Catalysts

OCT- clear

Phase 2

Preoperative Skin Preparation | Small molecule | Dermatology |Becton, Dickinson and Company|Last Updated: Apr 23, 2021

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment131

FDA Designations

No designations recorded

Clinical trial landscape

OCT- clear · 1 trial · 1 indication

Phase 2 1
NCT03224299Effectiveness of an Antimicrobial Agent for Preoperative Skin PreparationPreoperative Skin Preparation
COMPLETED131 Analytics
PHASE2COMPLETED
Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation
Preoperative Skin PreparationUnlock trial analytics

Study Endpoints

Primary Endpoints

Antimicrobial Activity of the Investigational Products Compared to Control.
10 minutes

Secondary Endpoints

Responder Rate at 6 Hours Post-application
6 hours
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposePREVENTION

Treatment Arms

ArmTypeDescription
Investigational Product #1 (IP1)EXPERIMENTALoctenidine dihydrochloride in isopropyl alcohol in a single-use applicator - clear
Investigational Product #2 (IP2)EXPERIMENTALoctenidine dihydrochloride in isopropyl alcohol in a single-use applicator - tinted
Active ControlACTIVE_COMPARATORChloraPrep® - Hi-Lite Orange® applicator
Negative ControlPLACEBO_COMPARATORsterile 0.9% saline applied with single use applicator

Interventions

NameTypeDescription
OCT - clearDRUGInvestigational Product #1: octenidine dihydrochloride in isopropyl alcohol in a single-use applicator - clear
OCT- tintedDRUGInvestigational product #2: octenidine dihydrochloride in isopropyl alcohol in a single-use applicator - tinted
ChloraPrepOTHERActive Control: ChloraPrep® - Hi-Lite Orange® applicator
SalineOTHERNegative Control: sterile 0.9% saline applied with single use applicator
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria: * Subjects may be of either sex, at least 18 years of age and of any race. * Subjects must be in good general health. * Subjects must read and sign an Informed Consent Form, Authorization to Use and Disclose Protected Health Information Form, and the List of Restricted Products ...

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about OCT- clear

What is OCT-clear used for?

OCT-clear is used for preoperative skin preparation, a procedure to reduce bacteria on the skin before surgery. It is being developed by Becton, Dickinson and Company (BDX) as a small molecule treatment in the dermatology therapeutic area. The drug is currently in Phase 2 clinical development.

What does OCT-clear target?

OCT-clear is a small molecule antimicrobial agent. Its specific molecular target has not been disclosed. The drug is designed for preoperative skin preparation to reduce microbial load on the skin prior to surgical procedures.

Who makes OCT-clear?

OCT-clear is developed by Becton, Dickinson and Company, a medical technology company traded on the New York Stock Exchange under the ticker BDX. The company is conducting clinical trials to evaluate the drug's effectiveness for preoperative skin preparation.

What phase is OCT-clear in?

OCT-clear is in Phase 2 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 2 trial has been completed, evaluating the drug's effectiveness for preoperative skin preparation in healthy volunteers.

What clinical trials is OCT-clear in?

OCT-clear has one completed clinical trial, NCT03224299, titled "Effectiveness of an Antimicrobial Agent for Preoperative Skin Preparation." This Phase 2 study enrolled 131 participants in the United States, was randomized, double-blind, and placebo-controlled, and included healthy volunteers aged 18 years and older.

Is OCT-clear the same as other names?

OCT-clear is the primary name for this investigational drug. No alternative names have been reported for this asset. It is being studied under the clinical trial identifier NCT03224299 for preoperative skin preparation.