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Vasovist · 1 trial · 1 indication
| Arm | Type | Description |
|---|---|---|
| Arm 1 | EXPERIMENTAL | - |
| Name | Type | Description |
|---|---|---|
| Vasovist (BAY86-5283, MS-325) | DRUG | All patients receive a single IV bolus injection of Vasovist at a dose of 0,03 mmol/kg BW at a flowrate of 0,5 mL/sec, followed by a saline flush of at least 30 mL |
Inclusion Criteria: * Patients with a certain circulation disorder (aortoiliac disease Fontaine-stage IIb / IV) and an indication for the evaluation of the peripheral run-off arteries from the infrarenal aorta to the calves * Patients who are scheduled for X-ray angiography and magnetic resonance a...
Vasovist is an investigational contrast agent developed for magnetic resonance angiography (MRA) in patients with peripheral vascular diseases, including peripheral artery disease. It is intended to help visualize blood vessels during MRA imaging. It is not approved for commercial use and remains in clinical development.
Vasovist is being developed by Bayer AG, a multinational pharmaceutical and life sciences company. Bayer's shares trade on the OTC market in the United States under the ticker BAYRY. The drug is part of Bayer's cardiovascular imaging portfolio.
Vasovist is in Phase 3 clinical development. One Phase 3 trial has been completed, and no active trials are currently recruiting. The drug is investigational and has not been approved by the FDA or any regulatory agency for commercial use.
Vasovist has been studied in one completed Phase 3 trial, NCT00296855, titled "Comparison Study of Vasovist Magnetic Resonance Angiography (MRA) and an MRA With a Conventional Extracellular Contrast Agent With X-ray Angiography in Patients With Peripheral Artery Disease." The trial enrolled 261 patients across Argentina, Austria, Brazil, Germany, Mexico, and Switzerland.
Yes, Vasovist is also known by the development codes BAY86-5283 and MS-325. These names refer to the same investigational contrast agent developed by Bayer AG for use in magnetic resonance angiography. The different codes reflect various stages of its development and licensing history.