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Skyla

Phase 3

Contraception | Small molecule | Endocrine |Bayer AG|Last Updated: Jul 27, 2015

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment304

FDA Designations

No designations recorded

Clinical trial landscape

Skyla · 1 trial · 1 indication

Phase 3 1
NCT01434160LCS12 Adolescent StudyContraception
COMPLETED304 Analytics
PHASE3COMPLETED
LCS12 Adolescent Study
ContraceptionUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of adverse events reported by study subjects
12 months treatment period
Portion of subjects reporting adverse events
12 months treatment period

Secondary Endpoints

Overall satisfaction rating from 1 to 5 (from very satisfied to very dissatisfied)
12 months treatment period
Pearl index
12 months treatment period
Bleeding patterns collected from patients' diary
12 months treatment period
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposePREVENTION

Treatment Arms

ArmTypeDescription
Arm 1EXPERIMENTAL -

Interventions

NameTypeDescription
Skyla (Levonorgestrel, BAY86-5028)DRUGLevonorgestrel intrauterine contraceptive system (LCS12) insertion into the uterus at insertion visit 2 with the study treatment of 12 months. An optional follow up phase up to 3 years will be offered for all subjects completing 12 month treatment time.
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Eligibility Criteria

Age Range12 Years to 17 Years
SexFEMALE
Healthy VolunteersYes
Study Sites41

Inclusion Criteria: * The subject has signed and dated the informed consent form (ICF) * The subject is female, generally healthy, post-menarcheal, nulliparous or parous, requiring contraception, and is under 18 years of age at the Screening visit * The subject has regular menstrual cycles without ...

Countries:AustriaBelgiumDenmarkFinlandGermanyNetherlandsNorwaySweden
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Frequently asked questions about Skyla

What is Skyla used for?

Skyla is a small molecule drug used for contraception. It is being developed by Bayer AG for use as a contraceptive method. The drug is currently in Phase 3 clinical development, meaning it is still investigational and has not yet been approved for marketing.

How does Skyla work?

Skyla is a small molecule drug. Its specific molecular target has not been disclosed in the available information, so the exact mechanism of action is not detailed here. It is being studied for its contraceptive effects.

Who makes Skyla?

Skyla is being developed by Bayer AG, a pharmaceutical company. Bayer AG is publicly traded under the ticker symbol BAYRY. The company is conducting clinical trials to evaluate Skyla for contraception.

What phase is Skyla in?

Skyla is in Phase 3 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The Phase 3 trial for Skyla has been completed, and the drug is being evaluated for use in contraception.

What clinical trials is Skyla in?

Skyla has one completed Phase 3 clinical trial, identified as NCT01434160, titled 'LCS12 Adolescent Study'. This trial enrolled 304 female participants aged 12 years and older across multiple European countries, including Austria, Belgium, Denmark, Finland, Germany, Netherlands, Norway, and Sweden. The study was uncontrolled and not randomized or double-blinded.

Is Skyla the same as any other drug?

Skyla is the name used in the clinical trial data provided. No alternative names for Skyla have been mentioned in the available information, so it is not known if it is marketed under other names.