Recent Updates
Recently added Catalysts

Campath-1H

Phase 2

Lymphoplasmacytic Lymphoma | Small molecule | Other |Bayer AG|Last Updated: Dec 21, 2012

Development status

Highest phase Phase 2
Registered trials 2 across 2 sponsors since Oct 2003

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment27

FDA Designations

No designations recorded

Clinical trial landscape

Campath-1H · 1 trial · 2 indications

Phase 2 1
NCT00142181Phase II Study of Campath-1H Antibody to Treat Waldenstrom's MacroglobulinemiaLymphoplasmacytic Lymphoma
COMPLETED27 Analytics
PHASE2COMPLETED
Phase II Study of Campath-1H Antibody to Treat Waldenstrom's Macroglobulinemia
Lymphoplasmacytic LymphomaUnlock trial analytics

Study Endpoints

Primary Endpoints

To determine the effectiveness of Campath-1H in treating patients with Waldenstrom's macroglobulinemia.
2 years

Secondary Endpoints

To determine the safety of Campath-1H.
2 years
Unlock Study Endpoints

Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Campath-1HEXPERIMENTAL30 mg IV three times a week, 6-12 weeks.

Interventions

NameTypeDescription
Campath-1HDRUGParticipant will receive three test doses of Campath-1H (3, 10, and 30mg). If this is tolerated then they will receive Campath-IH three times a week for 6 weeks.
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to 80 Years
SexALL
Healthy VolunteersNo
Study Sites3

Inclusion Criteria: * Diagnosis of lymphoplasmacytic lymphoma including patients with Waldenstrom's macroglobulinemia * Adequate organ function: ANC \> 500/ul; PLT \> 25,000/ul; serum creatinine \< 2.5; serum total bilirubin and SGOT \< 2.5 times the upper normal limit. * Age greater than 18 years ...

Countries:United States
Unlock Eligibility Criteria