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BAY86-5300

Phase 3

Contraception | Small molecule | Endocrine |Bayer AG|Last Updated: Oct 28, 2014

Success Probability

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Market & Valuation

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Trial Design

RandomizedCONTROLLED
Total Trials1
Total Enrollment508

FDA Designations

No designations recorded

Clinical trial landscape

BAY86-5300 · 1 trial · 1 indication

Phase 3 1
NCT01257984Study to Investigate Compliance With the Oral Contraceptive SH T00186D in a Flexible Extended Regimen Supported by a Dispenser With a Reminder FunctionContraception
COMPLETED508 Analytics
PHASE3COMPLETED
Study to Investigate Compliance With the Oral Contraceptive SH T00186D in a Flexible Extended Regimen Supported by a Dispenser With a Reminder Function
ContraceptionUnlock trial analytics

Study Endpoints

Primary Endpoints

Mean daily delay of tablet release, i.e. the time of tablet-release which will be compared to the reference tablet release time
12 months

Secondary Endpoints

Number of delayed and missed pills
12 months
Bleeding pattern and cycle control parameters
12 months
Length of the tablet break and the length of the bleeding episode preceding the tablet break
12 months
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Arm 1EXPERIMENTAL -
Arm 2EXPERIMENTAL -

Interventions

NameTypeDescription
BAY86-5300DRUG0.02 mg EE as ß-CDC / 3 mg DRSP in a tablet form (1 tablet/day) for up to 120 days, followed by a 4-day tablet-free interval, administered with a dispenser supported by a reminder function
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Eligibility Criteria

Age Range18 Years to 35 Years
SexFEMALE
Healthy VolunteersYes
Study Sites43

Inclusion Criteria: * Healthy female volunteers between 18 and 35 years of age (smokers up to 30 years, inclusive) who request contraceptive protection Exclusion Criteria: * Pregnancy or lactation (less than 3 months since delivery, abortion, or lactation before start of treatment) * Body mass in...

Countries:FranceGermanyItalySpainUnited Kingdom
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Frequently asked questions about BAY86-5300

What is BAY86-5300 used for?

BAY86-5300 is an investigational oral contraceptive being developed for contraception. It is a small molecule in the endocrine therapeutic area. As of the available data, it is in Phase 3 clinical development and has not been approved by regulatory authorities.

Who makes BAY86-5300?

BAY86-5300 is being developed by Bayer AG, which trades under the ticker BAYRY. The company is conducting clinical trials to evaluate the drug as an oral contraceptive.

What phase is BAY86-5300 in?

BAY86-5300 is in Phase 3 clinical development. One Phase 3 trial has been completed, with 508 participants enrolled. The drug remains investigational and is not yet approved for any use.

What clinical trials is BAY86-5300 in?

BAY86-5300 has one completed Phase 3 trial, NCT01257984, which studied compliance with the oral contraceptive SH T00186D in a flexible extended regimen supported by a dispenser with a reminder function. The trial enrolled 508 healthy female participants aged 18 years and older in France, Germany, Italy, Spain, and the United Kingdom.

Is BAY86-5300 the same as SH T00186D?

Yes, BAY86-5300 is also known as SH T00186D. The Phase 3 clinical trial NCT01257984 refers to the drug as SH T00186D, indicating that these names refer to the same investigational oral contraceptive.