Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00508495 | Analgesic Efficacy, Safety and Tolerability of Two Paracetamol-Containing Solutions in Post-Surgical Hip Replacement Pain | PHASE3 | COMPLETED | 148 | — | — | Aug 1, 2007 | Mar 1, 2008 | Aug 11, 2011 | 8 | Hungary |
| Arm | Type | Description |
|---|---|---|
| Test drug | EXPERIMENTAL | - |
| Reference drug | ACTIVE_COMPARATOR | - |
| Placebo | PLACEBO_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| Paracetamol (acetaminophen) | DRUG | Four 100 mL, 15 min IV infusions at six hour intervals |
| Paracetamol 1% solution | DRUG | Four 100 mL, 15 min IV infusions at six hour intervals |
| 0.9% sodium chloride solution | DRUG | Four 100 mL, 15 min IV infusions at six hour intervals |
Inclusion Criteria: * ASA I, II or III and scheduled for elective total hip replacement, using a standard approach and a cemented implant. * Moderate or severe pain within 4 hours after stopping the PCA in the morning of the first post-operative day. Exclusion Criteria: * Another acute or chronic...