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Hemopatch

Phase 2

Pancreas Cancer | Unknown | Oncology |Baxter International Inc.|Last Updated: Nov 3, 2021

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment52

FDA Designations

No designations recorded

Clinical trial landscape

Hemopatch · 1 trial · 7 indications

Phase 2 1
NCT03410914Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal PancreatectomyPancreas Cancer
COMPLETED52 Analytics
PHASE2COMPLETED
Intra-operative Application of HEMOPATCH to the Pancreatic Stump to Prevent Post-operative Pancreatic Fistula Following Distal Pancreatectomy
Pancreas CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of Participants With a Clinically Significant Post-operative Pancreatic Fistula (POPF)
Within 90 days post-operatively

Incidence of clinically-significant POPF - defined as ISGPS Grade B or C POPF. Determination of Grade B or C POPF was made on the basis of confirmation of presence of pancreatic fistula (any measurable volume of drain fluid on or after postoperative day 3, with an amylase content greater than 3 times the upper normal serum value) in conjunction with a review of participants' postoperative clinical course.

Secondary Endpoints

Number of Participants With a Post-operative Pancreatic Fistula (POPF)
Within 90 days post-operatively
Number of Participants Who Experienced Post-Operative Complications
Within 90 days post-operatively
90-Day Mortality Count
Within 90 days post-operatively
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposePREVENTION

Treatment Arms

ArmTypeDescription
HemopatchEXPERIMENTALApplication of hemopatch to the divided end of the pancreas during surgery

Interventions

NameTypeDescription
HemopatchDEVICEApplication of hemopatch to the divided end of the pancreas during surgery.
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites7

Inclusion Criteria: * Scheduled to undergo distal pancreatectomy surgery that is open or laparoscopic, with or without splenectomy * Age ≥ 18 years * Able and willing to comply with study procedures and follow-up examinations contained within the written consent form Exclusion Criteria: * Contrai...

Countries:Canada
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Frequently asked questions about Hemopatch

What is Hemopatch used for?

Hemopatch is an investigational surgical sealant being studied for use in prolonged air leak after lung resection and for preventing post-operative pancreatic fistula following distal pancreatectomy in patients with pancreas cancer and other pancreas diseases. It is developed by Baxter International Inc. and is currently in clinical development.

Who makes Hemopatch?

Hemopatch is developed by Baxter International Inc., a company traded on the New York Stock Exchange under the ticker BAX. The company is conducting clinical trials to evaluate the sealant's effectiveness in surgical settings.

What phase is Hemopatch in?

Hemopatch is in Phase 2 clinical development. One Phase 2 trial has been completed, and a Phase 3 trial has also been completed. The drug is investigational and has not been reported as FDA approved.

What clinical trials is Hemopatch in?

Hemopatch has been studied in two completed trials. NCT02491671 was a Phase 3 trial in Spain with 260 participants evaluating the sealant for preventing prolonged air leak after lung resection. NCT03410914 was a Phase 2 trial in Canada with 52 participants studying its use on the pancreatic stump after distal pancreatectomy.

Is Hemopatch the same as a tissue sealant?

Hemopatch is described as a novel tissue sealant in clinical trials. It is being evaluated for its effectiveness in preventing prolonged air leak after lung resection and for preventing post-operative pancreatic fistula. No other alternative names for Hemopatch have been reported.