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Aritinercept

Phase 1

Myasthenia Gravis, Generalized | Small molecule | Neurology |Aurinia Pharmaceuticals Inc|Last Updated: May 19, 2026

Success Probability
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Market & Valuation
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Trial Design
RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment81
FDA Designations
No designations recorded
Clinical trial landscape

Aritinercept · 1 trial · 1 indication

Phase 1 1
NCT07596901Study of Aritinercept in Patients With Generalized Myasthenia GravisMyasthenia Gravis, Generalized
RECRUITING81 Analytics
PHASE1RECRUITING
Study of Aritinercept in Patients With Generalized Myasthenia Gravis
Myasthenia Gravis, GeneralizedUnlock trial analytics
Study Endpoints
Primary Endpoints
To assess the safety and tolerability of aritinercept: Incidence of treatment-emergent adverse events
Baseline to study completion, up to 73 weeks
Secondary Endpoints
To assess the efficacy of aritinercept: Change from baseline in Myasthenia Gravis Activities of Daily Living (MG-ADL) total score
Baseline to 16 weeks
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Study Design & Arms
AllocationRANDOMIZED
MaskingQUADRUPLE
ModelSEQUENTIAL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
AritinerceptEXPERIMENTALDouble-Blind Treatment Period: Aritinercept by subcutaneous injection Open-Label Treatment Period: Aritinercept by subcutaneous injection
PlaceboPLACEBO_COMPARATORDouble-Blind Treatment Period: Placebo by subcutaneous injection Open-Label Treatment Period: Aritinercept by subcutaneous injection
Interventions
NameTypeDescription
AritinerceptDRUGFor subcutaneous injection
PlaceboOTHERFor subcutaneous injection
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Eligibility Criteria
Age Range18 Years to 85 Years
SexALL
Healthy VolunteersNo
Study Sites3

Key Inclusion Criteria: * Adult patients (18-85 years old) * Myasthenia Gravis Foundation of America (MGFA) Class II-IV gMG * Additional inclusion criteria are defined in the protocol Key Exclusion Criteria: * Current or medical history of malignancy within the last 5 years * Pregnant, breastfeed...

Countries:United States
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Recent Changes (Last 90 Days)
LOWMay 26, 2026NCT07596901primaryCompletionDate: changed
LOWMay 24, 2026NCT07596901studyFirstPostDate: changed
LOWMay 21, 2026NCT07596901NEW_TRIAL: changed
LOWMay 21, 2026NCT07596901NEW_TRIAL: changed