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Tranexamic Acid

Phase 3

Hemorrhagic Shock | Small molecule | Other |Arrowhead Pharmaceuticals, Inc.|Last Updated: Jul 30, 2024

Success Probability

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Market & Valuation

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Trial Design

NO_TREATMENT_CONTROLLEDBiomarker
Total Trials1
Total Enrollment200

FDA Designations

No designations recorded

Clinical trial landscape

Tranexamic Acid · 1 trial · 2 indications

Phase 3 1
NCT03469947California Prehospital and In Hospital Antifibrinolytic Therapy Via TXAHemorrhagic Shock
COMPLETED200 Analytics
PHASE3COMPLETED
California Prehospital and In Hospital Antifibrinolytic Therapy Via TXA
Hemorrhagic ShockUnlock trial analytics

Study Endpoints

Primary Endpoints

Survival at 24 hours
24 hours

Mortality at 24 hours

Survival at 48 hours
48 hours

Mortality at 48 hours

Survival at 28 days
28 days

Mortality at 28 days

Secondary Endpoints

Blood Transfusion
24 hours
Length of Hospital Stay
28 days
Adverse Events
28 days
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Prehospital Tranexamic AcidEXPERIMENTAL1 gram of Tranexamic Acid will be given during medical transport
Matched ControlsNO_INTERVENTIONRetrospective matched controls

Interventions

NameTypeDescription
Tranexamic AcidDRUG1 gram of prehospital Tranexamic Acid
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Eligibility Criteria

Age Range18 Years to 90 Years
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Blunt or penetrating trauma with signs and symptoms of hemorrhagic shock * Systolic blood pressure less than 90 mmHg at scene of injury, during air and/or ground medical transport, or on arrival to designated trauma centers * Any sustained blunt or penetrating injury within 3 ...

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Frequently asked questions about Tranexamic Acid

What is Tranexamic Acid used for?

Tranexamic Acid is used for hemorrhagic shock, a condition of severe blood loss that can occur after trauma injury. It is being studied as a treatment to help control bleeding in patients experiencing this life-threatening condition.

Who makes Tranexamic Acid?

Tranexamic Acid is being developed by Arrowhead Pharmaceuticals, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol ARWR.

What phase is Tranexamic Acid in?

Tranexamic Acid is in Phase 3 clinical development. It is an investigational drug and has not been approved by the FDA. The Phase 3 trial has been completed, but the drug remains under investigation for the treatment of hemorrhagic shock.

What clinical trials is Tranexamic Acid in?

Tranexamic Acid has one completed Phase 3 clinical trial with the identifier NCT03469947, titled 'California Prehospital and In Hospital Antifibrinolytic Therapy Via TXA'. This trial enrolled 200 participants with hemorrhagic shock and trauma injury.

Is Tranexamic Acid a small molecule?

Yes, Tranexamic Acid is a small molecule drug. It is being developed as a therapeutic agent for hemorrhagic shock and is administered to patients experiencing severe bleeding.