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Last traded Feb 2, 2026. This price is not current.
FDA decisions, readouts and PDUFA dates · scored by probability of approval
| Catalyst | Drug / Treatment | Stage | Prob. of Approval | Description | Drug Type | Therapeutic Area | Source |
|---|---|---|---|---|---|---|---|
PDUFA 2026 | Example Drug Treatment for example condition requiring FDA review | Phase 3 | Small Molecule | Oncology | - |
Dated clinical, regulatory and corporate events for Applied Therapeutics, Inc.
How APLT actually traded into and out of each decision
| Date | Drug | Catalyst | Stage | Reaction | Event Move % | Best Trade % |
|---|---|---|---|---|---|---|
| 2025-12-31 | Govorestat (AT-007) | NDA Submission | NDA |
| Drug | Indication | Phase | PTRS | rNPV | Status | Enroll | Velocity | Design | Est. Completion | ML Signal | Last Change |
|---|---|---|---|---|---|---|---|---|---|---|---|
| AT-007 Small moleculeCompletedNCT04117711 | Classic Galactosemia | Phase 2 | COMPLETED | 161 | Dec 14, 2021 |
Readouts, endpoints and source filings for every APLT program
| Drug Name | Indication | Phase | Date | Trial Results Summary | Title | Source |
|---|---|---|---|---|---|---|
| govorestat Priority | CMT-SORD | Phase 2/3 | 2025-05-18 | 37% (p=0.005) reduction of sorbitol in the sciatic nerve; statistically significant correlation between absolute reduction in sorbitol and change in 10MWRT and CMT-FOM Lower Limb domain at 12 months; statistically significant improvement in CMT-HI; statistically significant correlation between percent change in sorbitol and change in CMT-HI at 12 monthsRead More | Applied Therapeutics Presents Full 12-Month Clinical Results and New Topline Data from INSPIRE Phase 2/3 Trial of Govorestat in CMT-SORD in Late-Breaking Oral Presentation at the Peripheral Nerve Society 2025 Annual MeetingRead More |
| Insider | Side | Shares | Price | Value | Date |
|---|---|---|---|---|---|
| Kanter Stacy J.Director | Sell | -43,000 65,000 held | $0.11 | 12/16/2025 |
| Fund | % of Portfolio | Current MV | Shares Owned | Activity |
|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT LLC | 0 % (-100 %) | 755.00 K | 2.43 M |
| Expiry | Call Vol | Put Vol | Vol P/C | Call OI | Put OI | OI P/C | IV Call | IV Call OI-Wtd | IV Call Vol-Wtd | IV Put | IV Put OI-Wtd | IV Put Vol-Wtd |
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| Last | Vol | OI | Last | Vol | OI | |
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How APLT ranks across every disease it competes in