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Phenazopyridine

Phase 3

Pain | Small molecule | Nephrology |Amneal Pharmaceuticals, Inc.|Last Updated: Jan 29, 2013

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindPLACEBO_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment233
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01064024Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. PlaceboPHASE3 COMPLETED 233Dec 1, 2009Dec 1, 2010Jan 29, 20131 United States
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Study Endpoints
Primary Endpoints
proportion of subjects in each treatment group who demonstrate reduction in pain or burning when passing urine.
24 hrs after first dose and 48 hrs after second dose
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Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Phenazopyridine Hydrochloride Tablets, USP 200 mgACTIVE_COMPARATOR -
PlaceboPLACEBO_COMPARATORMatching placebo to the phenazopyridine hydrochloride tablets
Interventions
NameTypeDescription
Phenazopyridine HydrochlorideDRUGTablets, 200 mg, every 8 hours for 48 hours.
PlaceboDRUGTablets, every 8 hours for 48 hours
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Eligibility Criteria
Age Range18 Years — N/A
SexFEMALE
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Diagnosis of uncomplicated urinary tract infection (uUTI) * Must have one of the following uUTI diagnosis * Cystitis * Urethritis * A Positive urine dipstick test showing nitrate or leukocyte esterase (LE) * Negative pregnancy test (if applicable) * Must have one or both of th...

Countries:United States
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