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Phenazopyridine

Phase 3

Pain | Small molecule | Infectious Disease |Amneal Pharmaceuticals, Inc.|Last Updated: Jan 29, 2013

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment233

FDA Designations

No designations recorded

Clinical trial landscape

Phenazopyridine · 1 trial · 2 indications

Phase 3 1
NCT01064024Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. PlaceboPain
COMPLETED233 Analytics
PHASE3COMPLETED
Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. Placebo
PainUnlock trial analytics

Study Endpoints

Primary Endpoints

proportion of subjects in each treatment group who demonstrate reduction in pain or burning when passing urine.
24 hrs after first dose and 48 hrs after second dose
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Phenazopyridine Hydrochloride Tablets, USP 200 mgACTIVE_COMPARATOR -
PlaceboPLACEBO_COMPARATORMatching placebo to the phenazopyridine hydrochloride tablets

Interventions

NameTypeDescription
Phenazopyridine HydrochlorideDRUGTablets, 200 mg, every 8 hours for 48 hours.
PlaceboDRUGTablets, every 8 hours for 48 hours
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Eligibility Criteria

Age Range18 Years to N/A
SexFEMALE
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Diagnosis of uncomplicated urinary tract infection (uUTI) * Must have one of the following uUTI diagnosis * Cystitis * Urethritis * A Positive urine dipstick test showing nitrate or leukocyte esterase (LE) * Negative pregnancy test (if applicable) * Must have one or both of th...

Countries:United States
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Frequently asked questions about Phenazopyridine

What is Phenazopyridine used for?

Phenazopyridine is used for pain associated with urinary tract infections. It is a small molecule being developed by Amneal Pharmaceuticals, Inc. (AMRX) and is currently in Phase 3 clinical development as an investigational drug.

How does Phenazopyridine work?

Phenazopyridine is a small molecule that targets pain associated with urinary tract infections. It is being studied for its ability to relieve pain in this condition, though the specific molecular target is not detailed.

Who makes Phenazopyridine?

Phenazopyridine is being developed by Amneal Pharmaceuticals, Inc., which trades under the ticker AMRX. The company is conducting clinical trials to evaluate the drug's safety and efficacy for pain related to urinary tract infections.

What phase is Phenazopyridine in?

Phenazopyridine is in Phase 3 clinical development. It is an investigational drug and has not been approved by the FDA. A Phase 3 trial has been completed to assess its safety and efficacy.

What clinical trials is Phenazopyridine in?

Phenazopyridine has one completed Phase 3 trial, NCT01064024, which evaluated the safety and efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg versus placebo. The trial enrolled 233 female participants aged 18 years and older in the United States.

Is Phenazopyridine the same as Phenazopyridine Hydrochloride?

Phenazopyridine is the same as Phenazopyridine Hydrochloride, as indicated by the clinical trial title. The drug is being studied in tablet form at a 200 mg dose for pain associated with urinary tract infections.