Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
trospium chloride · 1 trial · 1 indication
| Arm | Type | Description |
|---|---|---|
| 400 mg TrIP | EXPERIMENTAL | - |
| 800 mg TrIP | EXPERIMENTAL | - |
| Placebo | PLACEBO_COMPARATOR | - |
| Name | Type | Description |
|---|---|---|
| trospium chloride inhalation powder (TrIP) | DRUG | - |
| Placebo | DRUG | - |
Inclusion Criteria: * Male or female COPD patients between the ages of 40 and 80 years * Smoking history of at least 10 pack years * Not currently using (or able to wash out of) any long acting bronchodilators Exclusion Criteria: * Candidate on a waiting list for surgery while on study * Using lo...
Trospium chloride is an investigational small molecule being studied for the treatment of Chronic Obstructive Pulmonary Disease (COPD). It is formulated as an inhalation powder and was evaluated in a Phase 1 clinical trial in patients with COPD. The drug is still in clinical development and is not approved for this use.
Trospium chloride is being developed by Alkermes plc, a biopharmaceutical company traded on the NASDAQ under the ticker symbol ALKS. The company conducted a Phase 1 clinical trial of the drug as an inhalation powder for Chronic Obstructive Pulmonary Disease.
Trospium chloride is in Phase 1 clinical development for Chronic Obstructive Pulmonary Disease. It has completed one Phase 1 trial, which enrolled 24 participants. The drug remains investigational and has not received FDA approval for any indication.
Trospium chloride has one completed clinical trial, NCT00465959, titled "Study of Trospium Chloride Inhalation Powder (TrIP) in Patients With Chronic Obstructive Pulmonary Disease." This Phase 1, randomized, double-blind, placebo-controlled trial enrolled 24 participants in the United States.
In clinical trial NCT00465959, trospium chloride is referred to as TrIP, which stands for Trospium Chloride Inhalation Powder. This is the formulation used in the Phase 1 study for Chronic Obstructive Pulmonary Disease. The drug is also known by its generic name, trospium chloride.