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antioxidants

Phase 2

Central Serous Chorioretinopathy | Small molecule | Other |Alcon Inc.|Last Updated: Dec 30, 2009

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

antioxidants · 1 trial · 1 indication

Phase 2 1
NCT00963131High-dose Antioxidants for Central Serous ChorioretinopathyCentral Serous Chorioretinopathy
COMPLETED60 Analytics
PHASE2COMPLETED
High-dose Antioxidants for Central Serous Chorioretinopathy
Central Serous ChorioretinopathyUnlock trial analytics

Study Endpoints

Primary Endpoints

visual acuity and central macular thickness
6 months

Secondary Endpoints

fluorescein leakage at the third month
6 months
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
antioxidant tabletsEXPERIMENTALthe study arm received antioxidant tablets (Icaps) for 3 months or until the resolution of the disease
placebo tabletsPLACEBO_COMPARATORthe control arm received placebo tablets for 3 months or until the resolution of the disease

Interventions

NameTypeDescription
antioxidants tabletsDRUGvitamin A 6600 IU, vitamin C 400 mg, vitamin E 150 IU, riboflavin 10 mg, zinc 60 mg, copper 4 mg, selenium 40 mg, manganese 4 mg and lutein/zeaxanthin 4000 micrograms.
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Eligibility Criteria

Age Range30 Years to 50 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. patients with acute central serous chorioretinopathy within 6 weeks of onset 2. age between 30-50 years 3. new or recurrent attack (the symptom-free period should longer than 6 months) 4. fluorescein angiography (FA) confirmed the diagnosis with the inkblot or smoke-stack lea...

Countries:Thailand
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Frequently asked questions about antioxidants

What is antioxidants used for in Central Serous Chorioretinopathy?

Antioxidants are being studied as a treatment for Central Serous Chorioretinopathy, a condition that causes fluid buildup under the retina. The investigational therapy is being evaluated in a Phase 2 clinical trial to assess its effects on this eye disorder.

Who makes antioxidants?

Alcon Inc. (NYSE: ALC) is developing antioxidants as an investigational treatment for Central Serous Chorioretinopathy. The company is conducting clinical research on this small molecule therapy to evaluate its potential in treating the condition.

What phase is antioxidants in?

Antioxidants are in Phase 2 clinical development for Central Serous Chorioretinopathy. The therapy is investigational and not yet approved, with one completed Phase 2 trial that enrolled 60 participants.

What clinical trials is antioxidants in?

Antioxidants are being studied in the clinical trial NCT00963131, titled "High-dose Antioxidants for Central Serous Chorioretinopathy." This Phase 2, randomized, double-blind, placebo-controlled study was conducted in Thailand and enrolled 60 participants aged 30 years and older.

Is antioxidants the same as high-dose antioxidants?

Yes, antioxidants are also referred to as high-dose antioxidants in clinical research. The Phase 2 trial NCT00963131 specifically evaluated high-dose antioxidants for Central Serous Chorioretinopathy, confirming this alternative name for the therapy.