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Triamcinolone Acetonide Injectable

Phase 3

Vitrectomy | Small molecule | Ophthalmology |Alcon Inc.|Last Updated: Apr 5, 2012

Target and mechanism

ModalitySmall molecule

Also known as Triamcinolone Acetonide Injectable Suspension

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

Triamcinolone Acetonide Injectable · 1 trial · 1 indication

Phase 3 1
NCT00532415Safety and Efficacy of Vitreous Delineating Agent During VitrectomyVitrectomy
COMPLETED60 Analytics
PHASE3COMPLETED
Safety and Efficacy of Vitreous Delineating Agent During Vitrectomy
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Study Endpoints

Primary Endpoints

Change in Mean Visualization Score at Post-Instillation from Pre-Instillation
Day 0

A video image of the posterior segment structures of the eye was taken before instillation of the test product and after. An independent masked reader evaluated the images and graded the degree of visualization on a 5-point scale ranging from 1 to 4 and anchored at the ends by "Not Visible (0)" and "Clearly Delineated (4)." The mean difference was calculated, and a higher number indicated increased visibility.

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Study Design & Arms

AllocationNA
MaskingSINGLE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
TriamcinoloneEXPERIMENTALApproximately 1-4 mg (0.025-0.1 cc) as needed for visualization during pars plana vitrectomy with or without membrane removal.

Interventions

NameTypeDescription
Triamcinolone Acetonide Injectable SuspensionDRUGApproximately 1-4 mg (0.025-0.1 cc) as needed for visualization during pars plana vitrectomy with or without membrane removal.
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Patients planning to undergo pars plana vitrectomy with good vision in the non-surgery eye. * Other protocol-defined inclusion criteria may apply. Exclusion Criteria: * Patients under 18. * Patients with previous vitrectomy, elevated intraocular pressure (IOP) and/or history...

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