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Travatan

Phase 3

Glaucoma, Open-angle | Small molecule | Ophthalmology |Alcon Inc.|Last Updated: Oct 7, 2011

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment502

FDA Designations

No designations recorded

Clinical trial landscape

Travatan · 1 trial · 2 indications

Phase 3 1
NCT00051168A Long-term Safety Study of Once-daily TravatanGlaucoma, Open-angle
COMPLETED502 Analytics
PHASE3COMPLETED
A Long-term Safety Study of Once-daily Travatan
Glaucoma, Open-angleUnlock trial analytics

Study Endpoints

Primary Endpoints

Mean Intraocular Pressure
At 5 years.

Mean IOP for the patient's worse eye at baseline was used in the secondary endpoint analysis. 2 consecutive IOP measurements for each eye were taken. If the 2 measurements for the same eye differ by 4 mmHg or less, the average of the measurements would be considered as the mean IOP for that eye. If the 2 measurements for the same eye differ by more than 4 mmHg, then a third measurement was to be taken. All IOP measurements were performed with a Goldmann applanation tonometer.

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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
TravatanEXPERIMENTALTravoprost (0.004%)

Interventions

NameTypeDescription
TravatanDRUGTravoprost (0.004%) 1 drop each eye once daily
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Adult patients of any race and either sex with chronic angle-closure glaucoma.

Countries:United States
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Frequently asked questions about Travatan

What is Travatan used for?

Travatan is a small molecule used for the treatment of glaucoma and open-angle glaucoma, as well as ocular hypertension. It is administered once daily and is being developed for ophthalmic use. The drug is currently in Phase 3 clinical development.

Who makes Travatan?

Travatan is being developed by Alcon Inc., a company traded under the ticker symbol ALC. Alcon is conducting clinical trials to evaluate the safety and efficacy of Travatan for the treatment of glaucoma and open-angle glaucoma.

What phase is Travatan in?

Travatan is in Phase 3 clinical development. It has completed one Phase 3 trial, which was a long-term safety study. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is Travatan in?

Travatan has one completed Phase 3 clinical trial, identified as NCT00051168. This study, titled 'A Long-term Safety Study of Once-daily Travatan,' enrolled 502 participants with glaucoma, open-angle glaucoma, or ocular hypertension in the United States.

Is Travatan FDA approved?

Travatan is not FDA approved. It is an investigational drug currently in Phase 3 clinical development. A Phase 3 safety study has been completed, but the drug has not yet received regulatory approval for the treatment of glaucoma or open-angle glaucoma.