Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT00796926 | Trial to Compare the Efficacy of Systane Ultra and Refresh Drop in the Treatment of Dry Eye in Asian Eyes | PHASE3 | COMPLETED | 30 | — | — | Jul 1, 2009 | Nov 1, 2010 | Oct 7, 2011 | 1 | Singapore |
Global score calculated from square root( square of (discomfort severityX Sqr(symptom frequency)) Scale from 0 to 100 higher value indicates more adverse symptoms each subscale severity or frequency also has same minimum and maximum
| Arm | Type | Description |
|---|---|---|
| Systane Ultra | EXPERIMENTAL | Used four times a day topically to each eye |
| Refresh | ACTIVE_COMPARATOR | Used four times a day topically to each eye |
| Name | Type | Description |
|---|---|---|
| Systane Ultra eyedrops | DRUG | Four times a day |
| Refresh eye drops | DRUG | Four times a day |
Inclusion Criteria: 1. Subject age is between 40 and 65 years old. 2. Corneal fluorescein staining present in at least one/five sectors of at least one cornea 3. At least one question out of 6 questions on dry eye symptom present often or all the time. based on the Salisbury Eye study by Oliver...