Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Systane Ultra eyedrops · 1 trial · 2 indications
Global score calculated from square root( square of (discomfort severityX Sqr(symptom frequency)) Scale from 0 to 100 higher value indicates more adverse symptoms each subscale severity or frequency also has same minimum and maximum
| Arm | Type | Description |
|---|---|---|
| Systane Ultra | EXPERIMENTAL | Used four times a day topically to each eye |
| Refresh | ACTIVE_COMPARATOR | Used four times a day topically to each eye |
| Name | Type | Description |
|---|---|---|
| Systane Ultra eyedrops | DRUG | Four times a day |
| Refresh eye drops | DRUG | Four times a day |
Inclusion Criteria: 1. Subject age is between 40 and 65 years old. 2. Corneal fluorescein staining present in at least one/five sectors of at least one cornea 3. At least one question out of 6 questions on dry eye symptom present often or all the time. based on the Salisbury Eye study by Oliver...
Systane Ultra is used for the treatment of xerophthalmia, commonly known as dry eye. It is an ophthalmology product developed by Alcon Inc. and is currently in Phase 3 clinical development for this condition.
Systane Ultra is a small molecule product that targets the ocular surface to relieve symptoms of dry eye. It is designed to provide lubrication and moisture to the eye, addressing the discomfort associated with xerophthalmia.
Systane Ultra is developed by Alcon Inc., a company traded on the stock exchange under the ticker symbol ALC. Alcon is focused on eye care products, including treatments for dry eye.
Systane Ultra is in Phase 3 clinical development. It is an investigational product for the treatment of dry eye, and it is not yet approved by regulatory authorities.
Systane Ultra has one completed Phase 3 clinical trial, identified as NCT00796926. This trial compared the efficacy of Systane Ultra with a control in treating dry eye in Asian eyes, enrolling 30 participants in Singapore.
Systane Ultra is not the same as Refresh Drop. In a clinical trial, Systane Ultra was compared against Refresh Drop as an active control to evaluate its efficacy in treating dry eye. They are separate products.