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Glaucoma therapy

Phase 2

Open-Angle Glaucoma | Small molecule | Cardiovascular |Alcon Inc.|Last Updated: Aug 5, 2008

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment -
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00069719Phase II Safety and Efficacy Study to Evaluate a Glaucoma Therapy in Open-Angle Glaucoma or Ocular Hypertension PatientsPHASE2 COMPLETED -Feb 1, 1999Aug 1, 2003Aug 5, 20081 United States
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Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
Glaucoma therapyDRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Adult subjects of either sex and any race with open-angle glaucoma or ocular hypertension; * logMAR visual acuity not worse than 0.6. Exclusion Criteria: * Clinically relevant ophthalmic or systemic conditions may be excluded.

Countries:United States
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Competitive Landscape -Open-Angle Glaucoma 9 trials