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Brinzolamide/Timolol

Phase 2

Open-angle Glaucoma | Small molecule | Cardiovascular |Alcon Inc.|Last Updated: Nov 18, 2016

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment88
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00326092A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular HypertensionPHASE2 COMPLETED 88May 1, 2006Aug 1, 2006Nov 18, 20161 United States
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Study Endpoints
Primary Endpoints
Ocular discomfort
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Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
Brinzolamide/TimololDRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Adults of either sex and any race diagnosed with open-angle glaucoma (with or without pseudoexfoliation or pigment dispersion component) Exclusion Criteria: * Under 18

Countries:United States
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Competitive Landscape -Open-Angle Glaucoma 9 trials