Recent Updates
Recently added Catalysts

guided radiotherapy

Phase 1

Cancer | Unknown | Oncology |Avalon GloboCare Corp.|Last Updated: Jun 15, 2025

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

UNCONTROLLEDDMC
Total Trials1
Total Enrollment99

FDA Designations

No designations recorded

Clinical trial landscape

guided radiotherapy · 1 trial · 1 indication

Phase 1 1
NCT05413473Northern Alberta Linac-MR Image-Guided Radiotherapy (Northern LIGHTs-2)Cancer
RECRUITING99 Analytics
PHASE1RECRUITING
Northern Alberta Linac-MR Image-Guided Radiotherapy (Northern LIGHTs-2)
CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Proportion of planned radiotherapy fractions that are administered, without clinically unacceptable interruptions, with the Alberta linac-MR P3 system.
Approximately 6 years

The total number of planned radiotherapy fractions that are administered, without clinically unacceptable interruptions, on the Alberta linac-MR P3 system. The study will track the number of planned fractions administered per participant without any significant interruptions or delays in their treatment.

Secondary Endpoints

Incidence of acute toxicity
6 months post treatment
Incidence of late toxicity
between 6 months and 2 years post treatment
Quantify the patient experience on the Linac-MR
1 year post treatment
Unlock Study Endpoints

Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
MR guided radiotherapyEXPERIMENTALMR-guided radiotherapy using the Alberta linac-MR P3 system. Contemporary radiotherapy techniques and fractionation schedules will be conducted in the following graduated stages with overlap between stages allowed: Stage 1: Parallel-opposed pair treatments (palliative) Stage 2: 4 field box treatments (curative or palliative) Stage 3: High dose treatments - multi-field 3DCRT (curative or palliative) Stage 4: High dose treatments - multi-field IMRT (curative or palliative)

Interventions

NameTypeDescription
MR guided radiotherapyDEVICEMR guided radiotherapy using the Alberta linac-MR P3 system
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Adults ≥ 18 years of age * Patients deemed fit to undergo external beam radiation therapy by their attending radiation oncologist * Accessible for follow-up Exclusion Criteria: * Patients with contraindications for MRI * Patients who are unable to lie flat and still for the ...

Countries:Canada
Unlock Eligibility Criteria

Frequently asked questions about guided radiotherapy

What is guided radiotherapy used for in cancer?

Guided radiotherapy is an investigational treatment approach being studied for use in cancer. It is currently in Phase 1 clinical development, meaning it is being evaluated for safety and feasibility in patients. The therapy is not yet approved and remains under investigation through an active clinical trial.

Who is developing guided radiotherapy?

Guided radiotherapy is being developed by Avalon GloboCare Corp., a biopharmaceutical company. The company is conducting clinical research on this investigational cancer treatment. Avalon GloboCare Corp. is publicly traded under the ticker symbol ALBT.

What phase is guided radiotherapy in?

Guided radiotherapy is currently in Phase 1 clinical development. This early-stage trial is designed to assess the safety and feasibility of the treatment approach in cancer patients. The study is actively recruiting participants, and the therapy remains investigational, meaning it has not yet received regulatory approval.

What clinical trials is guided radiotherapy in?

Guided radiotherapy is being evaluated in one active clinical trial, identified as NCT05413473, titled "Northern Alberta Linac-MR Image-Guided Radiotherapy (Northern LIGHTs-2)." This Phase 1 study is recruiting 99 adult participants with cancer in Canada. The trial is uncontrolled and not randomized or blinded.

Is guided radiotherapy FDA approved?

Guided radiotherapy is not FDA approved. It is an investigational treatment currently in Phase 1 clinical development for cancer. The therapy is being studied in an active clinical trial to evaluate its safety and feasibility, but it has not yet completed the clinical development process required for regulatory approval.