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Resource Support Plus

Phase 2

Malnourishment | Unknown | Other |Avalon GloboCare Corp.|Last Updated: Mar 28, 2025

Success Probability

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Trial Design

RandomizedNO_TREATMENT_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment81

FDA Designations

No designations recorded

Clinical trial landscape

Resource Support Plus · 1 trial · 3 indications

Phase 2 1
NCT05379712Nutritional Supplementation in Head and Neck CancersMalnourishment
RECRUITING81 Analytics
PHASE2RECRUITING
Nutritional Supplementation in Head and Neck Cancers
MalnourishmentUnlock trial analytics

Study Endpoints

Primary Endpoints

Change in mean cumulative energy intake
Up to 14 weeks

Energy intake is calculated from a one-day diet record in which the patient lists the identity and quantity of all foods and beverages consumed in the designated 24 hour time period at the end of each week (Baseline - Week 14).

Secondary Endpoints

Change in mean cumulative protein take
Up to 14 Weeks
Change in body weight (kg)
Baseline-Week 14
Change in Nutritional blood biomarkers
Baseline measures will be compared to levels at weeks 7 and 14
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Multimodal Nutrition TherapyEXPERIMENTALTo assess a multimodal nutrition therapy (primary nutrition intervention+ adjuvant nutrition therapy) with features adapted for patients with cancers of the head and neck receiving chemo-radiotherapy treatment, to maintain oral dietary intake during treatment. The regimen consists of 2 medical foods, each taken on an unrestricted basis (as and when preferred by each patient). Resource® Support Plus, a nutritionally complete Medical Food specifically for the dietary management of oncology patients with (risk of) malnutrition. BOOST® Soothe, a Medical Food formulated as a clear oral nutritional supplement for cancer patients with sensory alterations or oral discomfort due to cancer treatments, in particular chemo- and/or radiotherapy.
Standard of CareNO_INTERVENTIONIn this setting patients rely on oral dietary intake. Ordinary, commercially available ingredients and food products are consumed. The standard of care includes weekly consultation with specialist oncology Registered Dietitian.

Interventions

NameTypeDescription
Resource® Support PlusOTHERNestlé Resource Support Plus® is a high energy- and protein-density Medical Food enriched with omega 3 polyunsaturated fatty acids. This is a nutritionally complete formula, in an easy to swallow, palatable, concentrated low volume, available in 2 flavours optimized for cancer patients undergoing chemotherapy and/or radiation in taste tests. It provides in a 125 mL serving: 250 kcal, 11.5 g protein and 0.95g of omega-3 fatty acid (eicosapentaenoic acid, EPA).
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. Patients must have the ability to read, understand, and sign an informed consent and must be willing to comply with study treatment and follow-up. 2. Male or female 3. ≥18 years of age 4. Histopathologically confirmed primary squamous cell carcinoma of the oral cavity and oro...

Countries:Canada
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Frequently asked questions about Resource Support Plus

What is Resource Support Plus used for?

Resource Support Plus is an investigational nutritional supplement being studied for the treatment of malnourishment, nutritional deficiency, and undernutrition. It is currently in Phase 2 clinical development for these conditions.

Who makes Resource Support Plus?

Resource Support Plus is being developed by Avalon GloboCare Corp., a biopharmaceutical company traded under the ticker ALBT. The company is conducting a Phase 2 clinical trial to evaluate the supplement in patients with nutritional deficiencies.

What phase is Resource Support Plus in?

Resource Support Plus is in Phase 2 clinical development. It is an investigational product and has not been approved by regulatory authorities. A Phase 2 trial is currently recruiting participants to assess its effects on malnourishment and nutritional deficiency.

What clinical trials is Resource Support Plus in?

Resource Support Plus is being studied in a Phase 2 clinical trial with the identifier NCT05379712, titled "Nutritional Supplementation in Head and Neck Cancers." The trial is recruiting 81 participants in Canada and is open to adults aged 18 years and older.

Is Resource Support Plus a randomized trial?

Yes, the Phase 2 clinical trial of Resource Support Plus is randomized and uses a no-treatment control group. The study is not double-blinded, and it includes biomarker selection as part of its design. The trial is actively recruiting participants.