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Functional MRI imaging and tomotherapy

Phase 1

Glioblastoma | Unknown | Oncology |Avalon GloboCare Corp.|Last Updated: Feb 24, 2016

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDDMC
Total Trials1
Total Enrollment26

FDA Designations

No designations recorded

Clinical trial landscape

Functional MRI imaging and tomotherapy · 1 trial · 2 indications

Phase 1 1
NCT00250211Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and TemozolomideGlioblastoma
COMPLETED26 Analytics
PHASE1COMPLETED
Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide
GlioblastomaUnlock trial analytics

Study Endpoints

Primary Endpoints

determine tumor response and pattern of failure using functional MRI imaging
Study completion
time to disease progression
Study completion

Secondary Endpoints

distinguish residual tumor from treatment-related necrosis
study completion
survival
acute late toxicity of tomotherapy and hypofractionation
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
Functional MRI imaging and tomotherapyPROCEDURE -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Histologically confirmed glioblastoma multiforme * Ages 18-65 * Karnofsky Performance Scale (KPS) equal to or less than 70 * Minimal neurological deficit * Eligible for concurrent temozolomide chemotherapy Exclusion Criteria: * Prior radiation therapy to hand or neck area, c...

Countries:Canada
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Frequently asked questions about Functional MRI imaging and tomotherapy

What is Functional MRI imaging and tomotherapy used for in glioblastoma?

Functional MRI imaging and tomotherapy is an investigational imaging and treatment approach being studied for glioblastoma. It combines magnetic resonance spectroscopic imaging and tumor perfusion assessment with concurrent radiation therapy and temozolomide. The approach is in Phase 1 clinical development for glioblastoma and glioma.

Who is developing Functional MRI imaging and tomotherapy?

Functional MRI imaging and tomotherapy is being developed by Avalon GloboCare Corp., which trades under the ticker ALBT. The company is conducting clinical research on this imaging and treatment approach for glioblastoma.

What phase is Functional MRI imaging and tomotherapy in?

Functional MRI imaging and tomotherapy is in Phase 1 clinical development. It is an investigational approach and has not been approved by regulatory authorities. One Phase 1 clinical trial has been completed for this imaging and treatment strategy in glioblastoma.

What clinical trials is Functional MRI imaging and tomotherapy in?

Functional MRI imaging and tomotherapy has one completed clinical trial, NCT00250211, titled "Magnetic Resonance Spectroscopic Imaging (MRS) and Tumor Perfusion of Human Glioblastoma Treated With Concurrent Radiation Therapy and Temozolomide." This Phase 1 study enrolled 26 participants in Canada.

Is Functional MRI imaging and tomotherapy the same as magnetic resonance spectroscopic imaging?

Functional MRI imaging and tomotherapy refers to an approach that incorporates magnetic resonance spectroscopic imaging (MRS) and tumor perfusion assessment alongside radiation therapy. The clinical trial NCT00250211 specifically evaluates MRS and tumor perfusion in glioblastoma patients receiving concurrent radiation and temozolomide.