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Interferon alpha lozenge

Phase 2

Respiratory Tract Diseases | Small molecule | Respiratory |Ainos, Inc.|Last Updated: Apr 20, 2012

Target and mechanism

ModalitySmall molecule

Also known as Interferon alpha oral lozenge

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment18

FDA Designations

No designations recorded

Clinical trial landscape

Interferon alpha lozenge · 1 trial · 4 indications

Phase 2 1
NCT01442779Clinical Trial of Low Dose Oral Interferon Alpha in Idiopathic Pulmonary FibrosisRespiratory Tract Diseases
COMPLETED18 Analytics
PHASE2COMPLETED
Clinical Trial of Low Dose Oral Interferon Alpha in Idiopathic Pulmonary Fibrosis
Respiratory Tract DiseasesUnlock trial analytics

Study Endpoints

Primary Endpoints

Minimal/no Progression (1 yr) by High Resolution Computed Tomography (HRCT) & Pulmonary Function
1 yr

Disease progression was determined by comparing results of the High Resolution Computed Tomography(HRCT) and pulmonary function at one year to the baseline HRCT \& pulmonary function. The same radiologist did the comparsion for all subjects.

Minimal/no Change in Quality of Life
12 months

Secondary Endpoints

Participants With Change in Cough
1 month
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
Interferon alpha oral lozengeDRUGdose form - oral lozenge dose - 150 International Units (IU) frequency - 3 times a day duration - at least 1 year
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Eligibility Criteria

Age Range50 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * The only subjects to be included in this study are those diagnosed with Idiopathic Pulmonary Fibrosis with diagnosis based on the criteria published by the American Thoracic Society in the International Consensus Statement. 1. Exclusion of other known causes of interstitial...

Countries:United States
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Frequently asked questions about Interferon alpha lozenge

What is interferon alpha lozenge?

Interferon alpha lozenge is an orally administered formulation of interferon alpha developed by Ainos, Inc. under the ticker AIMD. It is being studied in respiratory tract diseases, including interstitial lung diseases such as idiopathic pulmonary fibrosis. The lozenge is a small molecule modality delivered orally rather than by injection.

What is interferon alpha lozenge used for?

Interferon alpha lozenge is being studied for respiratory tract diseases, specifically conditions including idiopathic pulmonary fibrosis and other interstitial lung diseases. The only recorded clinical trial enrolled adults aged 50 years and older with idiopathic pulmonary fibrosis. It is investigational and has not been established as a treatment for any condition.

Who makes interferon alpha lozenge?

Ainos, Inc., which trades under the ticker AIMD, is the developer of interferon alpha lozenge. The company is advancing the oral interferon alpha formulation as a clinical-stage asset in respiratory indications.

What phase is interferon alpha lozenge in?

Interferon alpha lozenge is in Phase 2 development. One Phase 2 trial has been completed, and no trials are currently active. The program remains investigational and is still in clinical development.

What clinical trials is interferon alpha lozenge in?

Interferon alpha lozenge has been evaluated in one completed Phase 2 trial, NCT01442779, titled Clinical Trial of Low Dose Oral Interferon Alpha in Idiopathic Pulmonary Fibrosis. That study enrolled 18 participants in the United States, was uncontrolled, and included adults aged 50 years and older.

Is interferon alpha lozenge the same as interferon alpha oral lozenge?

Yes, interferon alpha oral lozenge is another name for interferon alpha lozenge. Both names refer to the same Ainos, Inc. oral interferon alpha product candidate being studied in respiratory tract diseases, so readers searching either term are looking at the same asset.