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HSPPC-96 or Oncophage

Phase 3

Malignant Melanoma | Small molecule | Oncology |Agenus Inc.|Last Updated: Sep 7, 2012

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedUNCONTROLLEDBiomarker
Total Trials1
Total Enrollment350
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00039000Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV MelanomaPHASE3 COMPLETED 350Mar 1, 2002Dec 1, 2005Sep 7, 201277 United States, Australia +7
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
HSPPC-96 or OncophageDRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites77

Eligibility Assessment: (The following assessments must be obtained within three weeks prior to randomization into the study) * Medical history and physical examination (including EGOG score, evidence of immunosuppression); * CT/MRI of the chest, abdomen and pelvis; * Clinical examination; * CT/MR...

Countries:United StatesAustraliaHungaryItalyPolandRussiaSwedenUkraineUnited Kingdom
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