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HSPPC-96 or Oncophage

Phase 3

Malignant Melanoma | Small molecule | Oncology |Agenus Inc.|Last Updated: Sep 7, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment350

FDA Designations

No designations recorded

Clinical trial landscape

HSPPC-96 or Oncophage · 1 trial · 1 indication

Phase 3 1
NCT00039000Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV MelanomaMalignant Melanoma
COMPLETED350 Analytics
PHASE3COMPLETED
Study of Heat Shock Protein-Peptide Complex (HSPPC-96) Versus IL-2/DTIC for Stage IV Melanoma
Malignant MelanomaUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
HSPPC-96 or OncophageDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites77

Eligibility Assessment: (The following assessments must be obtained within three weeks prior to randomization into the study) * Medical history and physical examination (including EGOG score, evidence of immunosuppression); * CT/MRI of the chest, abdomen and pelvis; * Clinical examination; * CT/MR...

Countries:United StatesAustraliaHungaryItalyPolandRussiaSwedenUkraineUnited Kingdom
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Frequently asked questions about HSPPC-96 or Oncophage

What is HSPPC-96 (Oncophage) used for?

HSPPC-96, also known as Oncophage, is an investigational small molecule being studied for the treatment of malignant melanoma. It is a heat shock protein-peptide complex that is being evaluated in patients with stage IV melanoma. The drug is still in clinical development and has not been approved by regulatory authorities.

How does HSPPC-96 (Oncophage) work?

HSPPC-96, or Oncophage, is a heat shock protein-peptide complex. It is designed to stimulate the immune system to recognize and attack cancer cells by presenting tumor-specific peptides to immune cells. This mechanism is intended to generate an anti-tumor immune response in patients with malignant melanoma.

Who is developing HSPPC-96 (Oncophage)?

HSPPC-96, also known as Oncophage, is being developed by Agenus Inc., a biopharmaceutical company. Agenus is listed on the stock exchange under the ticker symbol AGEN. The company is conducting clinical trials to evaluate the drug's safety and efficacy in patients with malignant melanoma.

What phase is HSPPC-96 (Oncophage) in?

HSPPC-96, also known as Oncophage, is in Phase 3 clinical development. It is an investigational drug being studied for the treatment of malignant melanoma. The drug has not been approved by the FDA or other regulatory agencies and remains in clinical trials to assess its safety and effectiveness.

What clinical trials is HSPPC-96 (Oncophage) in?

HSPPC-96, also known as Oncophage, has one completed Phase 3 clinical trial with the identifier NCT00039000. This trial studied the drug versus IL-2/DTIC for stage IV melanoma and enrolled 350 participants across multiple countries, including the United States, Australia, and several European nations. The trial was randomized but not double-blinded.

Is HSPPC-96 the same as Oncophage?

Yes, HSPPC-96 and Oncophage refer to the same drug. HSPPC-96 is the chemical name, while Oncophage is the brand name used by the developer, Agenus Inc. Both names are used interchangeably in clinical research and publications related to the treatment of malignant melanoma.