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SN2310 Injectable Emulsion

Phase 1

Breast Neoplasms | Small molecule | Oncology |Achieve Life Sciences, Inc.|Last Updated: Jun 4, 2009

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment61

FDA Designations

No designations recorded

Clinical trial landscape

SN2310 Injectable Emulsion · 1 trial · 5 indications

Phase 1 1
NCT00385177Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid TumorsBreast Neoplasms
COMPLETED61 Analytics
PHASE1COMPLETED
Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid Tumors
Breast NeoplasmsUnlock trial analytics

Study Endpoints

Primary Endpoints

Maximum Tolerated Dose
December 2008
Dose-Limiting Toxicity
December 2008
Adverse Events
December 2008
Pharmacokinetic parameters for SN2310 and SN-38
December 2008
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
AEXPERIMENTALSN2310 Injectable Emulsion

Interventions

NameTypeDescription
SN2310 Injectable EmulsionDRUGEscalating doses given IV every three weeks
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Histologically or cytologically confirmed diagnosis of solid tumor with disease progression despite standard therapy and/or for which no other solid therapeutic option exists * ANC \> 1,500 cell/mm3, platelets \> 100,000/mm3 and Hgb \> 9 g/dl * At least one unidimensionally me...

Countries:United States
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Frequently asked questions about SN2310 Injectable Emulsion

What is SN2310 Injectable Emulsion used for?

SN2310 Injectable Emulsion is an investigational small molecule being studied for the treatment of breast neoplasms, or breast cancer. It was evaluated in patients with advanced solid tumors, including breast, colorectal, pancreatic, pelvic, and lung neoplasms, in a Phase 1 clinical trial.

What does SN2310 target?

SN2310 Injectable Emulsion is a small molecule, but its specific molecular target has not been disclosed. The drug was studied in a Phase 1 dose escalation trial for advanced solid tumors, including breast cancer, but the mechanism of action is not publicly detailed.

Who makes SN2310 Injectable Emulsion?

SN2310 Injectable Emulsion is being developed by Achieve Life Sciences, Inc., a company traded on the NASDAQ under the ticker symbol ACHV. The company conducted a Phase 1 clinical trial of the drug in patients with advanced solid tumors.

What phase is SN2310 Injectable Emulsion in?

SN2310 Injectable Emulsion is in Phase 1 clinical development. It has completed a Phase 1 dose escalation study, and the drug remains investigational, meaning it has not been approved by the FDA for any use.

What clinical trials is SN2310 Injectable Emulsion in?

SN2310 Injectable Emulsion has one completed clinical trial, NCT00385177, titled 'Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Advanced Solid Tumors.' The study enrolled 61 participants in the United States and was not randomized or blinded.

Is SN2310 Injectable Emulsion the same as any other drug?

SN2310 Injectable Emulsion is not known to have any alternative names. It is a distinct investigational drug developed by Achieve Life Sciences, Inc., and no other names for this asset have been reported.