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ACP-103

Phase 2

Hallucinations | Small molecule | Neurology |ACADIA Pharmaceuticals Inc.|Last Updated: Mar 22, 2007

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

ACP-103 · 2 trials · 4 indications

Phase 2 2
NCT00361166Antipsychotic and Motor Effects of ACP-103 When Administered in Combination With Haloperidol and RisperidoneSchizophrenia
COMPLETED400 Analytics
NCT00087542Treatment of Hallucinosis/Psychosis in Parkinson's Disease by an Investigational DrugHallucinations
COMPLETED60 Analytics
PHASE2COMPLETED
Antipsychotic and Motor Effects of ACP-103 When Administered in Combination With Haloperidol and Risperidone
SchizophreniaUnlock trial analytics
PHASE2COMPLETED
Treatment of Hallucinosis/Psychosis in Parkinson's Disease by an Investigational Drug
HallucinationsUnlock trial analytics

Study Endpoints

Primary Endpoints

Total score on the Positive and Negative Symptom Scale (PANSS).
ACP-103 is an effective treatment for Parkinson's Disease with psychosis

Secondary Endpoints

Clinical Global Impression-Severity (CGI-S), Simpson Angus Scale (SAS), Barnes Akathisia Scale (BAS), Calgary Depression Scale for Schizophrenia (CDSS)
ACP-103 does not cause worsening of motor function in Parkinson's Disease
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
ACP-103DRUG -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites17

Inclusion Criteria: * male or female subjects ages 18-65 diagnosed with schizophrenia * experiencing an acute exacerbation of psychosis * has had prior response to antipsychotic therapy within the previous 3 years * female subjects must be of non-childbearing potential or must comply with double-ba...

Countries:United StatesBrazil
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Frequently asked questions about ACP-103

What is ACP-103 used for?

ACP-103 is an investigational small molecule being studied for schizophrenia and hallucinations. It has been evaluated in Phase 2 clinical trials for these neurological conditions, including in patients with Parkinson's disease who experience hallucinations or psychosis.

Who makes ACP-103?

ACP-103 is being developed by ACADIA Pharmaceuticals Inc., a biopharmaceutical company traded on NASDAQ under the ticker symbol ACAD. The company is conducting clinical research to evaluate the drug's potential in treating schizophrenia and hallucinations.

What phase is ACP-103 in?

ACP-103 is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by regulatory authorities and is still undergoing clinical trials to assess its safety and efficacy for treating schizophrenia and hallucinations.

What clinical trials is ACP-103 in?

ACP-103 has been studied in two completed Phase 2 clinical trials. NCT00087542 evaluated the drug for hallucinations and psychosis in Parkinson's disease with 60 participants in the United States. NCT00361166 assessed its antipsychotic and motor effects when combined with haloperidol and risperidone in 400 participants with schizophrenia across the United States and Brazil.

Is ACP-103 the same as pimavanserin?

ACP-103 is also known by the name pimavanserin. It is being developed by ACADIA Pharmaceuticals for the treatment of schizophrenia and hallucinations, including hallucinations associated with Parkinson's disease.