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Phleum pratense grass pollen allergen extract · 1 trial · 1 indication
measurement of IgG4 in serum
| Arm | Type | Description |
|---|---|---|
| Grass tablet 75,000 SQ-T | EXPERIMENTAL | Grass tablet 75,000 Standardized Quality units Tablet (SQ-T) |
| Placebo | PLACEBO_COMPARATOR | Placebo |
| Name | Type | Description |
|---|---|---|
| Phleum pratense grass pollen allergen extract | DRUG | Allergy Immunotherapy grass tablet 75,000 SQ-T given once daily over 60 days |
| placebo | DRUG | placebo tablet given once daily over 60 days |
Inclusion Criteria: * clinical history consistent with grass pollen-induced allergic rhinoconjunctivitis. * Use of symptomatic treatment of grass pollen-induced allergic rhinoconjunctivitis. * Positive skin prick test response (wheal diameter ≥3 mm) to Phleum pratense. * If asthma, daily use of Inh...
Phleum pratense grass pollen allergen extract is used for seasonal allergic rhinitis, specifically grass pollen-induced allergic rhinoconjunctivitis. It is an investigational sublingual immunotherapy tablet being developed by Abbott Laboratories for the treatment of this condition.
Abbott Laboratories (NYSE: ABT) is developing Phleum pratense grass pollen allergen extract. The drug is being studied as a sublingual immunotherapy tablet for seasonal allergic rhinitis caused by grass pollen.
Phleum pratense grass pollen allergen extract is in Phase 3 clinical development. It is an investigational drug and has not been approved by the FDA. A Phase 3 trial has been completed to evaluate its immunology and safety.
Phleum pratense grass pollen allergen extract has one completed Phase 3 trial, NCT02245360. This study evaluated the immunology and safety of 60-day treatment with SQ grass SLIT-tablet in 107 adult subjects with grass pollen-induced allergic rhinoconjunctivitis in Russia.
Phleum pratense grass pollen allergen extract is a sublingual immunotherapy that works by exposing the immune system to grass pollen allergens. This exposure is intended to induce immune tolerance and reduce allergic responses to grass pollen, thereby alleviating symptoms of seasonal allergic rhinitis.