Recent Updates
Recently added Catalysts

Cortiment

Phase 1

Healthy Subjects | Small molecule | Other |Abbott Laboratories|Last Updated: Aug 29, 2022

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials1
Total Enrollment56
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT05519514Bio-Equivalence Study of Budesonide Prolonged-release Tablets 9 Mg In Healthy Human Adult SubjectsPHASE1 COMPLETED 56Jul 12, 2021Nov 15, 2021Aug 29, 20221 India
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Bioequivalence of Test Product (T) Vs Reference Product (R) Pharmacokinetic parameters: Cmax (Maximum plasma concentration)
Till 72 hours post dose after each dosing

Cmax (Maximum plasma concentration)

Bioequivalence of Test Product (T) Vs Reference Product (R) Pharmacokinetic Parameters: AUC0-t (area under the curve)
Till 72 hours post dose after each dosing

AUC0-t (area under the curve)

Secondary Endpoints
Safety and tolerability of Test Product (T) and the Reference Product (R) Serious adverse events
Till 30 days since last dosing period
Safety and tolerability of Test Product (T) and the Reference Product (R) Systolic and diastolic blood pressure
Till 72 hours post dose after each dosing
Safety and tolerability of Test Product (T) and the Reference Product (R) Pulse rate
Till 72 hours post dose after each dosing
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Cortiment (Budesonide 9 mg prolonged release tablet)ACTIVE_COMPARATOR -
Budesonide 9 mg prolonged release tabletEXPERIMENTAL -
Interventions
NameTypeDescription
CortimentDRUGBudesonide 9 mg prolonged release tablets
BudesonideDRUGExperimental (Budesonide 9 mg prolonged release tablets)
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 45 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Normal healthy human adult male and non- pregnant female volunteers between 18-45 years (both ages inclusive) of age. 2. Who is given written informed consent and are willing to participate in the study. 3. Body Mass Index of 18.50 to 30.00 Kg/m2 (both inclusive). 4. No evide...

Countries:India
Unlock Eligibility Criteria