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ABT-894

Phase 2

Attention-Deficit/Hyperactivity Disorder | Small molecule | Psychiatry |Abbott Laboratories|Last Updated: Nov 2, 2010

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment243

FDA Designations

No designations recorded

Clinical trial landscape

ABT-894 · 1 trial · 2 indications

Phase 2 1
NCT00429091A Dose-Ranging Study of the Efficacy of ABT-894 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)Attention-Deficit/Hyperactivity Disorder
COMPLETED243 Analytics
PHASE2COMPLETED
A Dose-Ranging Study of the Efficacy of ABT-894 in Adults With Attention-Deficit/Hyperactivity Disorder (ADHD)
Attention-Deficit/Hyperactivity DisorderUnlock trial analytics

Study Endpoints

Primary Endpoints

CAARS:Inv Total Score (Sum of Inattentive and Hyperactive/Impulsive Sub-scales)
Final Evaluation of each 4-week Treatment Period

Secondary Endpoints

CAARS Inattentive and Hyperactive/Impulsive Sub-scales Scores
Final Evaluation of each 4-week Treatment Period
CAARS ADHD Index
Final Evaluation of each 4-week Treatment Period
CGI-ADHD-S
Final Evaluation of each 4-week Treatment Period
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelCROSSOVER
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1PLACEBO_COMPARATOR -
2EXPERIMENTAL -
3ACTIVE_COMPARATOR -

Interventions

NameTypeDescription
ABT-894DRUGSubjects will take 1 mg QD, 2 mg QD, 4 mg QD, 4 mg BID for up to four weeks.
atomoxetineDRUGSubjects will take 40 mg BID or placebo for up to four weeks.
placeboDRUGSubjects will take BID for up to four weeks
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Eligibility Criteria

Age Range18 Years to 60 Years
SexALL
Healthy VolunteersNo
Study Sites22

Inclusion Criteria: * Meet criteria for attention-deficit/hyperactivity disorder * Have voluntarily signed an informed form * Are between 18 and 60 years of age * Will use contraceptive methods during the study * Women must not be pregnant or breast-feeding * Must be in generally good health * Are ...

Countries:United States
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Frequently asked questions about ABT-894

What is ABT-894 used for?

ABT-894 is an investigational small molecule being studied for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in adults. It is in Phase 2 clinical development and is not yet approved by regulatory authorities.

Who makes ABT-894?

ABT-894 is being developed by Abbott Laboratories, a company traded on the New York Stock Exchange under the ticker symbol ABT. The drug is currently in Phase 2 clinical trials for adult ADHD.

What phase is ABT-894 in?

ABT-894 is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by the FDA or other regulatory agencies. One Phase 2 trial has been completed, and the drug remains under investigation for adult ADHD.

What clinical trials is ABT-894 in?

ABT-894 has one completed Phase 2 clinical trial, identified as NCT00429091. This was a dose-ranging study evaluating the efficacy of ABT-894 in adults with Attention-Deficit/Hyperactivity Disorder. The trial enrolled 243 participants in the United States and was randomized, double-blind, and placebo-controlled.

Is ABT-894 the same as any other drug?

No alternative names for ABT-894 have been disclosed. The drug is identified solely by its code name ABT-894 in clinical trial records and is being developed by Abbott Laboratories for adult ADHD.