Recent Updates
Recently added Catalysts

ABT-510/Thrombospondin-1 mimetic

Phase 2

Carcinoma, Renal Cell | Small molecule | Oncology |Abbott Laboratories|Last Updated: Aug 15, 2007

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedUNCONTROLLEDBiomarker
Total Trials1
Total Enrollment103
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00073125Safety and Efficacy of ABT-510 in Subjects With Advanced Renal Cell CarcinomaPHASE2 COMPLETED 103May 1, 2003 -Aug 15, 200718 United States, Netherlands
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Progression free survival
One year
Secondary Endpoints
Response rate
One year
Overall survival
One year
Performance status
One year
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingSINGLE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
ABT-510/Thrombospondin-1 mimeticDRUG -
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites18

Inclusion Criteria: A subject will be eligible for study participation if all of the following criteria are met: * The subject is at least 18 years of age. * The subject has advanced histologically documented renal cell carcinoma. Advanced disease is defined as locally recurrent disease or metasta...

Countries:United StatesNetherlands
Unlock Eligibility Criteria