Recent Updates
Recently added Catalysts

EcoNail

Phase 2

Onychomycosis | Small molecule | Infectious Disease |Abeona Therapeutics Inc.|Last Updated: Sep 3, 2020

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment40

FDA Designations

ORPHAN_DRUG

Clinical trial landscape

EcoNail · 1 trial · 1 indication

Phase 2 1
NCT00385502A Trial of the Safety and Efficacy of EcoNail™ in the Treatment of Fungus Infections of the Great ToenailOnychomycosis
COMPLETED40 Analytics
PHASE2COMPLETED
A Trial of the Safety and Efficacy of EcoNail™ in the Treatment of Fungus Infections of the Great Toenail
OnychomycosisUnlock trial analytics

Study Endpoints

Primary Endpoints

Determine effectiveness of EcoNail™ lacquer, as determined by effects on nail mycology and appearance, when applied daily for 48 weeks to diseased great toenails in subjects with onychomycosis.
Week 48

Secondary Endpoints

Evaluate the safety and local tolerability of EcoNail™ lacquer under the same circumstances.
Week 56
Unlock Study Endpoints

Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
EcoNail™EXPERIMENTALeconazole 5%/SEPA® 18% nail lacquer

Interventions

NameTypeDescription
EcoNail™ (econazole 5%/SEPA® 18% nail lacquer)DRUGnail lacquer applied daily for 48 weeks
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites3

Inclusion Criteria: * Subjects who are men and women greater than or equal to 18 years of age and less than or equal to 65 years of age. * Female subjects who are post-menopausal (amenorrheic for at least 1 year), surgically sterile, have a partner with a vasectomy, or routinely using an acceptable...

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about EcoNail

What is EcoNail used for?

EcoNail is an investigational small molecule being developed for the treatment of onychomycosis, a fungal infection of the nail. It is currently in Phase 2 clinical development and has not been approved by the FDA.

Who makes EcoNail?

EcoNail is being developed by Abeona Therapeutics Inc. (NASDAQ: ABEO). The company is conducting clinical trials to evaluate the safety and efficacy of this investigational treatment for onychomycosis.

What phase is EcoNail in?

EcoNail is in Phase 2 clinical development. It is an investigational drug and has not been approved by the FDA. One Phase 2 trial has been completed, and the drug has received orphan drug designation.

What clinical trials is EcoNail in?

EcoNail has one completed Phase 2 clinical trial, NCT00385502, which evaluated its safety and efficacy in treating fungus infections of the great toenail. The trial enrolled 40 participants in the United States and was not randomized or blinded.

Is EcoNail FDA approved?

No, EcoNail is not FDA approved. It is an investigational drug currently in Phase 2 clinical development for onychomycosis. It has received orphan drug designation from the FDA, but it has not completed the approval process.