Financials
Cash Data
- Cash FlowProfitable
- SEC Filing
Key Stats
Upcoming Catalysts
FDA decisions, readouts and PDUFA dates · scored by probability of approval
ABBV Catalyst Timeline
Dated clinical, regulatory and corporate events for AbbVie Inc.
Catalyst Timeline
Dated clinical, regulatory & corporate events for AbbVie Inc.
Upcoming catalysts 2
Event history 50
Past FDA Catalysts and PDUFA Decisions
How ABBV actually traded into and out of each decision
| Date | Drug | Catalyst | Stage | Reaction | Event Move % | Best Trade % |
|---|---|---|---|---|---|---|
| 2026-10-23 | ABBV-969 | Phase 1 data presentation | Phase 1 |
Drug Pipeline Intelligence
| Product | Revenue | Prior period | Change |
|---|---|---|---|
| SKYRIZI | |||
| RINVOQ | |||
| Botox Therapeutic | |||
| Vraylar | |||
| HUMIRA | |||
| VENCLEXTA | |||
| Botox Cosmetic | |||
| Imbruvica | |||
| Creon | |||
| Ubrelvy | |||
| MAVYRET | |||
| Qulipta |
| Drug | Indication | Phase | PTRS | rNPV | Status | Enroll | Velocity | Design | Est. Completion | ML Signal | Last Change |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ABBV-1480 Small moleculeNCT07756645 | Non-Small Cell Lung Cancer | Phase 3 | RECRUITING | 940 | Dec 1, 2029 | ||||||
| ABBV-706 Small moleculeNCT07155174 | Small Cell Lung Cancer | Phase 3 | RECRUITING | 711 | Sep 1, 2031 | ||||||
| ABBV-706 Small moleculeNCT05599984 | Advanced Solid Tumors | Phase 1 | ACTIVE NOT_RECRUITING | 288 | Nov 1, 2027 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT06464692 | Colorectal Cancer | Phase 3 | ACTIVE NOT_RECRUITING | 1,161 | Dec 1, 2027 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT07821684 | Non-Squamous Non-Small Cell Lung Cancer | Phase 3 | NOT YET_RECRUITING | 1,514 | Apr 1, 2031 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT06614192 | Metastatic Colorectal Cancer | Phase 2 | ACTIVE NOT_RECRUITING | 464 | Aug 1, 2027 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT07196644 | Solid Tumors Harboring MET Amplification | Phase 2 | RECRUITING | 100 | Dec 1, 2030 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT07155187 | Non-Small Cell Lung Cancer | Phase 2 | RECRUITING | 490 | Sep 1, 2030 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT06628310 | Locally Advanced Unresectable or Metastatic Gastric Adenocarcinoma | Phase 2 | ACTIVE NOT_RECRUITING | 185 | Oct 1, 2030 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT07769502 | Pancreatobiliary Cancers | Phase 2 | RECRUITING | 168 | Sep 1, 2028 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT07744126 | Head and Neck Squamous Cell Carcinoma | Phase 2 | RECRUITING | 150 | Oct 1, 2029 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT07490301 | Metastatic Pancreatic Ductal Adenocarcinoma | Phase 2 | RECRUITING | 900 | Jun 1, 2031 | ||||||
| ABBV-400 Small moleculeNCT06107413 | Unresectable Metastatic Colorectal Cancer | Phase 2 | ACTIVE NOT_RECRUITING | 280 | Dec 1, 2026 | ||||||
| ABBV-400 Small moleculeNCT05029882 | Non-Small Cell Lung Cancer | Phase 1 | ACTIVE NOT_RECRUITING | 520 | Nov 1, 2027 | ||||||
| Telisotuzumab Adizutecan Monoclonal antibodyNCT06772623 | Non Small Cell Lung Carcinoma | Phase 1 | RECRUITING | 252 | Nov 1, 2027 | ||||||
| ABBV-400 Small moleculeNCT06084481 | Hepatocellular Carcinoma | Phase 1 | RECRUITING | 325 | Sep 1, 2027 | ||||||
| Etentamig Small moleculeNCT07793422 | Amyloid Light Chain (AL) Amyloidosis | Phase 3 | NOT YET_RECRUITING | 370 | Dec 1, 2034 | ||||||
| Etentamig Small moleculeNCT07728188 | Relapsed or Refractory Multiple Myeloma | Phase 3 | NOT YET_RECRUITING | 520 | Feb 1, 2033 | ||||||
| Etentamig Small moleculeNCT06223516 | Multiple Myeloma | Phase 3 | ACTIVE NOT_RECRUITING | 2,108 | Dec 1, 2027 | ||||||
| ABBV-383 Small moleculeNCT06158854 | Immunoglobulin Light Chain (AL) Amyloidosis | Phase 1 | RECRUITING | 76 | Aug 1, 2031 | ||||||
| TNB-383B Small moleculeNCT03933735 | Multiple Myeloma | Phase 1 | ACTIVE NOT_RECRUITING | 220 | May 1, 2026 | ||||||
| Etentamig Small moleculeNCT05286229 | Relapsed/Refractory Multiple Myeloma | Phase 1 | ACTIVE NOT_RECRUITING | 291 | Mar 1, 2026 | ||||||
| Surabgene Lomparvovec Gene therapyNCT04514653 | Neovascular Age-related Macular Degeneration | Phase 3 | ACTIVE NOT_RECRUITING | 707 | Feb 1, 2027 | ||||||
| Surabgene Lomparvovec Gene therapyNCT04704921 | AMD | Phase 3 | ACTIVE NOT_RECRUITING | 1,406 | Nov 1, 2027 | ||||||
| Surabgene Lomparvovec Gene therapyNCT04567550 | Diabetic Retinopathy | Phase 2 | ACTIVE NOT_RECRUITING | 715 | Dec 1, 2026 |
Clinical Trial Results
Readouts, endpoints and source filings for every ABBV program
| Drug Name | Indication | Phase | Date | Trial Results Summary | Title | Source |
|---|---|---|---|---|---|---|
| lutikizumab | hidradenitis suppurativa | Phase 3 | 2026-10-22 | primary endpoint: 31.4% versus 23.4%; p≤0.001; NRS3: 26.2% versus 15.0%; p<0.0001; NRS30: 36.0% versus 22.8%; p<0.0001; HS flares: 18.4% versus 28.1%; p<0.0001Read More | AbbVie Announces Topline Results from the Phase 3 INTREPID Trial Showing Lutikizumab Significantly Improved Signs and Symptoms of Disease in Patients with Hidradenitis SuppurativaRead More |
Inside Trades
| Insider | Side | Shares | Price | Value | Date |
|---|---|---|---|---|---|
| Donoghoe NicholasOfficer (EVP, CHIEF BUS/STRAT OFFICER) | Option | 32,710 107,140 held | $79.02 | 08/14/2026 |
Hedge Fund 13F Activity
Hedge Funds invested in ABBV
| Fund | % of Portfolio | Current MV | Shares Owned | Activity |
|---|---|---|---|---|
| PARKMAN HEALTHCARE PARTNERS LLC | 1.7 % (-22.7 %) | 16.31 M | 75.00 K | 64% ( 29.27 K) |
ABBV Institutional Ownership Trends
ABBV Short Interest
Shares sold short, counted twice a month.
Options Data
Option Volume
Option Chain Statistics
| Expiry | Call Vol | Put Vol | Vol P/C | Call OI | Put OI | OI P/C | IV Call | IV Call OI-Wtd | IV Call Vol-Wtd | IV Put | IV Put OI-Wtd | IV Put Vol-Wtd |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-10-30 | ||||||||||||
Real-Time Option Chain
| Calls | Strike | Puts | ||||
|---|---|---|---|---|---|---|
| Last | Vol | OI | Last | Vol | OI | |
| No data available | ||||||
Calls vs Puts by Expiry
Competitive positioning
How ABBV ranks across every disease it competes in
ABBV News
AbbVie Submits Biologics License Application (BLA) for Etentamig to U.S. FDA for Adults Living With Relapsed/Refractory Multiple Myeloma
AbbVie submitted a Biologics License Application for etentamig, a bispecific antibody for relapsed/refractory multiple myeloma. The Phase 3 CERVINO study demonstrated significant improvements in overall response rate and progression-free survival. The drug aims to provide a patient-centered treatment option with a manageable safety profile and monthly dosing.
Read more →U.S. FDA Approves Subcutaneous Induction Regimen for AbbVie's SKYRIZI® (risankizumab-rzaa) for Adults With Moderately to Severely Active Crohn's Disease
AbbVie announced FDA approval for a subcutaneous induction regimen of SKYRIZI for adults with moderately to severely active Crohn's disease. The approval is based on the Phase 3 AFFIRM study, showing superior clinical remission and endoscopic response at week 12 compared to placebo. Patients can now initiate treatment at home using an on-body injector device.
Read more →AbbVie Announces Topline Results from the Phase 3 INTREPID Trial Showing Lutikizumab Significantly Improved Signs and Symptoms of Disease in Patients with Hidradenitis Suppurativa
AbbVie announced positive topline results from the Phase 3 INTREPID study, where lutikizumab significantly improved signs and symptoms in patients with moderate to severe hidradenitis suppurativa. The study met its primary endpoint of HiSCR75 at Week 16 and demonstrated notable improvements in pain and flare occurrences. Lutikizumab was well tolerated with no new safety concerns.
Read more →AbbVie Presents Data for ABBV-466, a Novel Dual-Targeting Therapy Demonstrating Higher Endoscopic Remission Rates Than Either Anti-IL-23 or Anti-α4β7 Monotherapy in Moderate to Severe Crohn's Disease
AbbVie announced positive results from its Phase 2a study of ABBV-466, a dual-targeting therapy for moderate to severe Crohn's disease. The therapy achieved higher endoscopic remission rates at Week 12 compared to existing monotherapies. Gene expression analysis indicated significant intestinal repair and metabolic changes. These findings will be presented at the 2026 UEGW Congress.
Read more →AbbVie to Present Data at the 2026 European Society for Medical Oncology (ESMO) Congress Highlighting Progress Across its Expanding Solid Tumor Portfolio
AbbVie will showcase new data at the 2026 ESMO Congress, focusing on its solid tumor portfolio. The presentations will cover seven assets across various cancers, highlighting advancements in treatment approaches and promising clinical outcomes. Notably, Temab-A has shown encouraging results in colorectal and lung cancers, reinforcing AbbVie's commitment to oncology innovation.
Read more →AbbVie Presents New Phase 3 AFFIRM Data Showing Clinical and Endoscopic Outcomes With Subcutaneous SKYRIZI® (risankizumab-rzaa) in Patients With Moderately to Severely Active Crohn's Disease
AbbVie presented new Phase 3 AFFIRM study data showing that subcutaneous SKYRIZI (risankizumab-rzaa) significantly improves endoscopic remission and ulcer-free endoscopy rates in patients with moderately to severely active Crohn's disease. The findings indicate that 35.8% of patients achieved endoscopic remission after treatment, with even higher rates in therapy-naïve patients. This data supports AbbVie's application to the FDA for a new induction dosing regimen.
Read more →AbbVie's Telisotuzumab Adizutecan (Temab-A) Receives Two Breakthrough Therapy Designations From the U.S. FDA for CRC and NSCLC
AbbVie announced that its investigational drug, telisotuzumab adizutecan (Temab-A), has received two Breakthrough Therapy Designations from the FDA for colorectal cancer and non-small cell lung cancer. These designations underscore the drug's potential as a treatment for patients with advanced solid tumors. Temab-A is being studied both as a monotherapy and in combination with other therapies.
Read more →AbbVie and Genmab Announce Epcoritamab in Combination with R-CHOP Demonstrates Significant Improvement in Progression-Free Survival versus R-CHOP in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma
AbbVie and Genmab announced positive topline results from the Phase 3 EPCORE DLBCL-2 trial, which evaluated the bispecific antibody epcoritamab combined with R-CHOP in newly diagnosed diffuse large B-cell lymphoma (DLBCL) patients. The trial demonstrated a 51% reduction in the risk of disease progression or death, indicating a significant improvement in progression-free survival. The companies plan to engage global regulatory authorities based on these results.
Read more →Genmab and AbbVie Announce Epcoritamab in Combination with R-CHOP Demonstrates Statistically Significant Improvement in Progression-Free Survival in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma
Genmab and AbbVie announced positive topline results from the Phase 3 EPCORE DLBCL-2 trial, demonstrating that the bispecific antibody epcoritamab in combination with R-CHOP significantly improves progression-free survival in newly diagnosed DLBCL patients. The study showed a 51% reduction in the risk of disease progression or death. The companies plan to engage global regulatory authorities based on these findings.
Read more →AbbVie Presents Long-Term RINVOQ® (upadacitinib) Data Showing Continued Repigmentation in Non-Segmental Vitiligo
AbbVie presented long-term data on RINVOQ (upadacitinib) at the 2026 EADV Congress, demonstrating sustained facial and total body repigmentation in non-segmental vitiligo patients through week 76. The Phase 3 Viti-Up studies indicated improved outcomes when RINVOQ was combined with NB-UVB phototherapy. Safety results remained consistent with previous findings, with no new safety concerns reported.
Read more →AbbVie to Host Third-Quarter 2026 Earnings Conference Call
AbbVie will announce its third-quarter 2026 financial results on October 30, 2026, before market opening. A live webcast of the earnings conference call will take place at 8 a.m. Central time, accessible via AbbVie's Investor Relations website. An archived version will be available later that day.
Read more →AbbVie Presents Detailed Phase 1 Data for ABBV-295, a Long-Acting Amylin Analog, Demonstrating Favorable Tolerability and Pharmacokinetic Profile at EASD 2026
AbbVie presented detailed Phase 1 data for ABBV-295, a long-acting amylin analog, at the EASD 2026 Annual Meeting. The study showed favorable pharmacokinetics, including a half-life of approximately 11-12 days, and demonstrated meaningful weight loss across multiple dosing regimens. The results support advancing ABBV-295 into Phase 2 development for chronic weight management.
Read more →AbbVie Highlights Positive Results from the Phase 2 APEX Part B Study of Zumilokibart in Moderate to Severe Atopic Dermatitis, as a Late Breaker at EADV 2026
AbbVie announced positive results from the Phase 2 APEX Part B study of zumilokibart for moderate to severe atopic dermatitis. All dose regimens met the primary endpoint, with significant improvements in skin lesions and itch. The mid-dose regimen has been selected for Phase 3 development, supporting its potential as a long-term treatment option.
Read more →AbbVie Showcases Leadership in Dermatology Research With New Clinical and Real-World Evidence Across Immune-Mediated Skin Diseases at 2026 EADV Congress
AbbVie showcased its leadership in dermatology research at the 2026 EADV Congress, presenting 60 abstracts across various immune-mediated skin diseases. Key findings included new data on risankizumab and upadacitinib, which support their efficacy and safety. Investigational therapies lutikizumab and zumilokibart were also highlighted, indicating AbbVie's commitment to advancing treatment options for patients.
Read more →AbbVie Partners with Valkai to Apply Advanced AI Across Targeted Areas of Clinical Development
AbbVie has partnered with Valkai to enhance its artificial intelligence capabilities in clinical development. This collaboration aims to streamline research processes, generate insights more rapidly, and ultimately improve patient outcomes. The initiative reflects AbbVie's commitment to integrating AI throughout its drug development journey, leveraging advanced technology alongside human expertise.
Read more →Ginkgo Datapoints and Apheris Welcome AbbVie, argenx, Lundbeck, and Takeda as Founding Members of the Antibody Developability Consortium
Ginkgo Datapoints and Apheris have announced the inclusion of AbbVie, argenx, Lundbeck, and Takeda as founding members of the Antibody Developability Consortium. This collaboration aims to enhance the development processes for antibodies, leveraging the expertise of these leading biopharma companies. The consortium is expected to drive innovation in the field.
Read more →U.S. FDA Approves AbbVie's JUVMO™ (tavapadon) for Parkinson's Disease
The U.S. FDA has approved AbbVie's JUVMO™ (tavapadon) as the first selective D1/D5 receptor agonist for adults with Parkinson's disease. This novel treatment offers a new approach to managing motor symptoms and has shown significant efficacy in clinical trials, reducing the need for increased doses of oral levodopa. JUVMO is expected to be available to patients in October 2026.
Read more →UChicago Medicine completes construction phase of AbbVie Foundation Cancer Pavilion, bringing new era of cancer care closer to reality
The University of Chicago Medicine has completed the construction of the AbbVie Foundation Cancer Pavilion, a 575,000-square-foot facility dedicated to cancer care. Set to open in April 2027, this project aims to enhance access to advanced cancer treatments and improve health outcomes in underserved communities. The pavilion will serve approximately 200,000 outpatient visits and 5,000 inpatient admissions annually.
Read more →EPKINLY® receives Health Canada Approval for Adults with Follicular Lymphoma
AbbVie announced that Health Canada has approved EPKINLY® for adults with relapsed or refractory follicular lymphoma. This treatment, in combination with lenalidomide and rituximab, has shown a 79% reduction in the risk of disease progression or death in clinical trials. The approval highlights the need for effective therapies for a disease that is often incurable.
Read more →AbbVie Announces European Commission Approval of RINVOQ® (upadacitinib) for the Treatment of Children with Active Polyarticular Juvenile Idiopathic Arthritis
AbbVie has received European Commission approval for RINVOQ (upadacitinib) to treat active polyarticular juvenile idiopathic arthritis (pJIA) in children aged two and older who have not responded adequately to DMARDs. The approval is based on the SELECT-YOUTH Phase 1 study, demonstrating significant efficacy and safety. RINVOQ is now approved for 11 indications in the EU, expanding treatment options for pediatric patients.
Read more →