| Colorectal Cancer | #1 of 82 | PHASE 3
| Telisotuzumab Adizutecan | BMY MRK JNJ | $7.68B | 0.88 | LEADER
|
| Rheumatoid Arthritis | #1 of 28 | PHASE 3
| Upadacitinib + Adalimumab | LLY BMY JNJ | $4.2B | 0.92 | LEADER
|
| Hidradenitis Suppurativa | #1 of 13 | PHASE 3
| Lutikizumab | INCY NVS MLTX | $1.7B | 0.91 | LEADER
|
| Migraine | #1 of 5 | PHASE 3
| Atogepant | PFE LLY AMGN | $7.02B | 0.95 | LEADER
|
| Age-Related Macular Degeneration | #1 of 13 | PHASE 3
| Surabgene Lomparvovec + Ranibizumab Control | OCUL FDMT REGN | $15.43B | 0.91 | LEADER
|
| Dry Eye Disease | #1 of 7 | PHASE 3
| ABBV-444 + REFRESH OPTIVE UD | GRFS BLCO VNDA | $6.61B | 0.93 | LEADER
|
| Reproductive Endocrine | #1 of 7 | PHASE 3
| Elagolix + Combined Contraceptive | EDAP ABT ·dev MDT ·dev | — | 0.91 | LEADER
|
| Ocular Hypertension | #1 of 4 | PHASE 3
| Bimatoprost | SGP AMRX GKOS | $9.41B | 0.91 | LEADER
|
| Retinal Disorders | #1 of 4 | PHASE 2
| ABBV-RGX-314 + Ranibizumab | PRQR ALC UBX | — | 0.91 | LEADER
|
| Polycystic Kidney Disease | #1 of 3 | PHASE 2
| ABBV-CLS-628 | VRTX AZN | $1.76B | 0.88 | LEADER
|
| Multiple Myeloma | #2 of 27 | PHASE 3
| Pomalidomide + Dexamethasone + Venetoclax | JNJ BMY TAK | $23.78B | 0.88 | LEADER
|
| Atopic Dermatitis | #2 of 25 | PHASE 3
| Upadacitinib + corticosteroids | LLY PFE SNY | $20.76B | 0.92 | LEADER
|
| Myelodysplastic Syndromes | #2 of 33 | PHASE 3
| Venetoclax + Azacitidine | BMY TAK ARGX | $2.5B | 0.93 | CONTENDER
|
| Myeloproliferative Neoplasms | #2 of 14 | PHASE 3
| Navitoclax + Ruxolitinib | BMY NVS KPTI | — | 0.84 | CONTENDER
|
| Psoriatic Arthritis | #2 of 13 | PHASE 3
| Risankizumab | JNJ BMY TAK | — | 0.91 | LEADER
|
| Glaucoma | #2 of 7 | PHASE 3
| Bimatoprost | GKOS SGP AMRX | $8.99B | 0.92 | CONTENDER
|
| Bipolar Disorder | #2 of 12 | PHASE 3
| Cariprazine | BMY ALKS XENE | $10.5B | 0.91 | CONTENDER
|
| Irritable Bowel Syndrome | #2 of 6 | PHASE 3
| Eluxadoline | ARDX IRON TAK | $1.44B | 0.91 | CONTENDER
|
| Diabetic Retinopathy | #2 of 5 | PHASE 2
| ABBV-RGX-314 Dose 1 + Steroid + Aflibercept | OCUL FDMT RYTM | $10.29B | 0.95 | CONTENDER
|
| Crohn's Disease | #3 of 15 | PHASE 3
| Risankizumab + Risankizumab On-Body Injector | SNY LLY JNJ | $12.67B | 0.91 | LEADER
|
| Psoriasis | #3 of 15 | PHASE 3
| Risankizumab | JNJ BMY TAK | $26.66B | 0.95 | CONTENDER
|
| Alopecia | #3 of 12 | PHASE 3
| Upadacitinib | PFE MANE LLY | $10.76B | 0.91 | CONTENDER
|
| Vasculitis | #3 of 16 | PHASE 3
| Upadacitinib + Prednisolone | AZN GSK AMGN | $2.5B | 0.85 | CONTENDER
|
| Vitiligo | #3 of 8 | PHASE 3
| Upadacitinib | INCY PFE TAK | $1.2B | 0.93 | CONTENDER
|
| Open-Angle Glaucoma | #3 of 5 | PHASE 4
| Bimatoprost | GKOS AMRX UTHR | $8.99B | 0.93 | CONTENDER
|
| Ovarian Cancer | #4 of 61 | PHASE 3
| Mirvetuximab soravtansine plus Bevacizumab + Bevacizumab | MRK AZN LLY | $4.0B | 0.86 | LEADER
|
| Ulcerative Colitis | #4 of 17 | PHASE 3
| Upadacitinib | SNY JNJ LLY | $6.5B | 0.9 | LEADER
|
| Major Depressive Disorder | #4 of 31 | PHASE 3
| Cariprazine | CMPS NBIX JNJ | $12.0B | 0.94 | CONTENDER
|
| Anxiety Disorders | #4 of 12 | PHASE 2
| ABBV-932 + Antidepressant Therapy | DFTX VTGN VNDA | — | 0.95 | CONTENDER
|
| Idiopathic Pulmonary Fibrosis | #4 of 12 | PHASE 2
| ABBV-142 | BMY UTHR PRTC | $4.87B | 0.95 | CONTENDER
|
| Diabetic Macular Edema | #4 of 11 | PHASE 2
| ABBV-RGX-314 Dose 1 + Steroid + Aflibercept | EYPT REGN OCS | $4.2B | 0.95 | CONTENDER
|
| Geographic Atrophy | #5 of 8 | PHASE 1
| ABBV-6628 + SYFOVRE | REGN BLTE ANNX | $2.12B | 0.91 | CONTENDER
|
| Non-Small Cell Lung Cancer | #6 of 88 | PHASE 3
| Telisotuzumab Vedotin + Docetaxel | MRK AMGN AZN | $28.1B | 0.87 | LEADER
|
| Leukemia | #6 of 64 | PHASE 3
| Venetoclax | AMGN LLY AZN | $4.28B | 0.89 | LEADER
|
| Pancreatic Cancer | #6 of 73 | PHASE 2
| TTX-030, nab-paclitaxel and gemcitabine + Nab-Paclitaxel and gemcitabine | RVMD RCUS AZN | $3.7B | 0.82 | CONTENDER
|
| Liver Cancer | #6 of 37 | PHASE 2
| Budigalimab + Livmoniplimab + Lenvatinib + Sorafenib | AZN BMY EXEL | $4.8B | 0.85 | CONTENDER
|
| Systemic Lupus Erythematosus | #6 of 32 | PHASE 3
| Upadacitinib | BIIB VTRS BMY | $2.78B | 0.88 | CONTENDER
|
| Thyroid Disorders | #6 of 11 | PHASE 2
| Armour Thyroid + Levothyroxine | VRDN AMGN ZLAB | $11.1B | 0.91 | FOLLOWER
|
| Lung Cancer | #8 of 79 | PHASE 3
| ABBV-706 + Topotecan + Lurbinectedin + Amrubicin | MRK GILD AMGN | $28.1B | 0.89 | LEADER
|
| Esophageal Cancer | #8 of 39 | PHASE 2
| Telisotuzumab Adizutecan + Budigalimab + Fluorouracil + Leucovorin + Oxaliplatin | MRK AZN ONC | $1.85B | 0.85 | CONTENDER
|
| Schizophrenia | #8 of 15 | PHASE 2
| Emraclidine | NBIX BMY ALKS | $2.5B | 0.95 | FOLLOWER
|
| Amyloidosis | #8 of 11 | PHASE 1
| ABBV-383 | AZN NTLA JNJ | $5.17B | 0.89 | FOLLOWER
|
| Lymphoma | #9 of 69 | PHASE 3
| Venetoclax | REGN LLY MRK | $8.52B | 0.83 | CONTENDER
|
| Gastric Cancer | #10 of 49 | PHASE 2
| Telisotuzumab Adizutecan + Budigalimab + Fluorouracil + Leucovorin + Oxaliplatin | AZN ONC JAZZ | $6.74B | 0.88 | FOLLOWER
|
| Cervical Cancer | #12 of 31 | PHASE 1
| IMGN151 | AZN MRK PFE | $2.8B | 0.85 | FOLLOWER
|
| Obesity | #19 of 33 | PHASE 1
| ABBV-295 | LLY AMGN NVO | $22.52B | 0.97 | FOLLOWER
|
| Bladder Cancer | #19 of 47 | PHASE 2
| Livmoniplimab + Budigalimab + Docetaxel + Paclitaxel + Gemcitabine | AZN BMY JNJ | $0.33B | 0.9 | FOLLOWER
|
| Endometrial Cancer | #21 of 48 | PHASE 1
| IMGN151 | MRK AZN GILD | $31.09B | 0.85 | FOLLOWER
|
| Prostate Cancer | #22 of 53 | PHASE 1
| ABBV-969 | MRK AZN PFE | $25.12B | 0.9 | FOLLOWER
|
| Head and Neck Cancer | #22 of 63 | PHASE 1
| ABBV-400 + Itraconazole | AZN GSK MRK | $10.2B | 0.8 | FOLLOWER
|
| Breast Cancer | #27 of 94 | PHASE 1
| ABBV-400 + Itraconazole | MRK AZN GILD | $10.85B | 0.84 | FOLLOWER
|