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NOA VOLUME, VOLUMA XC

Phase 3

Mid Face Volume Deficit | Unknown | Other |AbbVie Inc.|Last Updated: Jun 18, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment231

FDA Designations

No designations recorded

Clinical trial landscape

NOA VOLUME, VOLUMA XC · 1 trial · 1 indication

Phase 3 1
NCT06734351A Study to Evaluate Safety and Effectiveness of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Improvement of Mid-Face VolumeMid Face Volume Deficit
RECRUITING231 Analytics
PHASE3RECRUITING
A Study to Evaluate Safety and Effectiveness of NOA VOLUME Injectable Gel in Adult Participants Compared to JUVÉDERM VOLUMA XC for Improvement of Mid-Face Volume
Mid Face Volume DeficitUnlock trial analytics

Study Endpoints

Primary Endpoints

Percentage of Participants Achieving "Responder" Status Based on the Evaluating Investigator's (EI) Live Assessment of Mid-Face Volume Deficit Scale (MFVDS)
Month 6

A "responder" is defined as a participant with at least 1-point improvement (reduction) of mid face volume deficit using the MFVDS. MFVDS is a validated 5-point scale (1 = None/Minimal to 5 = Severe).

Number of Participants with Adverse Events (AEs)
Up to Approximately Month 31

An AE is defined as any untoward medical occurrence in a patient or clinical investigation participant administered a pharmaceutical product which does not necessarily have a causal relationship with this treatment.

Secondary Endpoints

Change from Baseline in the Overall Score of FACE-Q Satisfaction with Cheeks
Month 6
Percentage of Participants Achieving "Responder" Status Based on Participant's Assessments of Global Aesthetic Improvement in the Treatment Area Using Global Aesthetic Improvement Scale (GAIS)
Month 6
Percentage of Participants Achieving "Responder" Status Based on EI's Assessments of Global Aesthetic Improvement in the Treatment Area Using the GAIS
Month 6
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Cohort 1: NOA VOLUMEEXPERIMENTALParticipants will receive NOA VOLUME on Day 1 with optional touch-up treatment on Day 31 and Month 18.
Cohort 1: VOLUMA XCEXPERIMENTALParticipants will receive VOLUMA XC on Day 1 with optional touch-up treatment on Day 31 and Month 18.
Cohort 2: NOA VOLUMEEXPERIMENTALParticipants will receive NOA VOLUME on Day 1 with optional touch-up treatment on Day 31 and Month 18.
Cohort 2: VOLUMA XCEXPERIMENTALParticipants will receive VOLUMA XC on Day 1 with optional touch-up treatment on Day 31 and Month 18.

Interventions

NameTypeDescription
NOA VOLUMEDEVICEInjections
VOLUMA XCDEVICEInjections
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Eligibility Criteria

Age Range22 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites15

Inclusion Criteria: * Has moderate (3), significant (4), or severe (5) mid-face volume deficit on the 5-point photonumeric MFVDS based on evaluating investigator's (EI) live assessment. * Mid-face is amenable to achieving at least a 1-point improvement in MFVDS score with the allowed injection volu...

Countries:United States
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Recent Changes (Last 90 Days)

LOWJun 18, 2026NCT06734351lastUpdatePostDate: changed
LOWJun 18, 2026NCT06734351lastUpdatePostDate: changed
LOWJun 18, 2026NCT06734351lastUpdatePostDate: changed

Frequently asked questions about NOA VOLUME, VOLUMA XC

What is NOA VOLUME, VOLUMA XC used for?

NOA VOLUME, VOLUMA XC is an injectable gel being studied for the improvement of mid-face volume deficit in adults. It is currently in Phase 3 clinical development and is not yet approved by the FDA. The product is being evaluated for safety and effectiveness in a clinical trial setting.

Who makes NOA VOLUME, VOLUMA XC?

NOA VOLUME, VOLUMA XC is being developed by AbbVie Inc., which trades under the ticker symbol ABBV. The company is conducting a Phase 3 clinical trial to evaluate the product's safety and effectiveness for mid-face volume deficit.

What phase is NOA VOLUME, VOLUMA XC in?

NOA VOLUME, VOLUMA XC is in Phase 3 clinical development. It is an investigational product and has not been approved by the FDA. The ongoing Phase 3 trial is recruiting participants to assess its safety and effectiveness for mid-face volume deficit.

What clinical trials is NOA VOLUME, VOLUMA XC in?

NOA VOLUME, VOLUMA XC is being studied in a Phase 3 clinical trial with the identifier NCT06734351. This randomized, double-blind, controlled study is evaluating the safety and effectiveness of NOA VOLUME injectable gel compared to JUVÉDERM VOLUMA XC for improvement of mid-face volume in adults.

Is NOA VOLUME, VOLUMA XC the same as JUVÉDERM VOLUMA XC?

NOA VOLUME, VOLUMA XC is being studied in comparison to JUVÉDERM VOLUMA XC in a clinical trial. The trial is designed to evaluate whether NOA VOLUME is as safe and effective as JUVÉDERM VOLUMA XC for improving mid-face volume. They are distinct products being compared in the study.