Recent Updates
Recently added Catalysts

Motexafin Gadolinium

Phase 3

Brain Neoplasms | Small molecule | Oncology |AbbVie Inc.|Last Updated: May 8, 2007

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedUNCONTROLLEDBiomarker
Total Trials1
Total Enrollment550
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00054795Study of Neurologic Progression With Motexafin Gadolinium and Radiation Therapy (SMART)PHASE3 COMPLETED 550 - -May 8, 200792 United States, Australia +6
Unlock Drug Trial Details
Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeTREATMENT
Interventions
NameTypeDescription
Motexafin GadoliniumDRUG -
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites92

Inclusion Criteria: * Adults (≥18 years old) with radiologically proven parenchymal brain metastases from histologically confirmed non-small cell lung cancer; * KPS score of ≥70; * Each patient must sign a study-specific Informed Consent form Exclusion Criteria: * Liver metastases; * Extracranial...

Countries:United StatesAustraliaAustriaBelgiumCanadaFranceGermanyNetherlands
Unlock Eligibility Criteria