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ARTIA Reconstructive Tissue Matrix

Phase 3

Breast Reconstruction | Unknown | Other |AbbVie Inc.|Last Updated: Jun 1, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDDMC
Total Trials1
Total Enrollment264
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT06575192Evaluation of the Safety and Effectiveness of ARTIA Reconstructive Tissue Matrix Breast Reconstruction (ADORA) in Adult ParticipantsPHASE3 RECRUITING 264Nov 5, 2024Feb 1, 2031Jun 1, 202622 United States
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Study Endpoints
Primary Endpoints
Occurrence of at Least One Major Complication related to Breast Reconstruction After Stage 1
Month 18

Number of participants with at least one major complication related to breast reconstruction.

Number of Participants with Adverse Events (AEs)
Up to Approximately 36 Months

An AE is defined as any untoward medical occurrence in a patient or clinical investigation in which a participant is administered a medical device which does not necessarily have a causal relationship with this treatment.

Secondary Endpoints
Occurrence of Reconstructive Failure Per Breast After Stage 1
Month 18
Change from Baseline in BREAST-Q Satisfaction with Breasts Score from Pre-Mastectomy After Stage 2
Up to Month 18
Occurrence of Capsular Contracture per Breast
Month 36
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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Acellular Dermal MatrixEXPERIMENTALBreast reconstruction with ARTIA Tissue Matrix.
Interventions
NameTypeDescription
ARTIA Reconstructive Tissue MatrixDEVICESurgical Implant
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Eligibility Criteria
Age Range18 Years — N/A
SexFEMALE
Healthy VolunteersNo
Study Sites22

Inclusion Criteria: * Participants who will undergo unilateral or bilateral mastectomy upon enrollment. * Participants who are willing and able to undergo immediate prepectoral, implant based, two-stage breast reconstruction with ARTIA. Exclusion Criteria: * Has an existing carcinoma of the breas...

Countries:United States
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Recent Changes (Last 90 Days)
HIGHJun 2, 2026NCT06575192Enrollment: 783 → 264
HIGHJun 2, 2026NCT06575192Enrollment: 783 → 264
HIGHJun 2, 2026NCT06575192Enrollment: 783 → 264
LOWMay 26, 2026NCT06575192primaryCompletionDate: changed
LOWMay 24, 2026NCT06575192studyFirstPostDate: changed