Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
ABBV-7828 · 1 trial · 1 indication
An adverse event (AE) is defined as any untoward medical occurrence in a clinical investigation participant administered a pharmaceutical product which does not necessarily have a causal relationship with this treatment. The investigator assesses the relationship of each event to the use of study.
Cmax of ABBV-7828
Beta of ABBV-7828
AUCt of ABBV-7878
AUCinf of ABBV-7878
| Arm | Type | Description |
|---|---|---|
| Part 1: ABBV-7828 | EXPERIMENTAL | Participants will receive single doses of ABBV-7828. |
| Part 1: Placebo | PLACEBO_COMPARATOR | Participants will receive single doses of placebo. |
| Part 2: ABBV-7828 Sequence 1 | EXPERIMENTAL | Participants will receive ABBV-7828 while in fasting in Period 1 followed by ABBV-7828 after high fat/high calorie meal in Period 2. |
| Part 2: ABBV-7828 Sequence 2 | EXPERIMENTAL | Participants will receive ABBV-7828 after a high-fat/high calorie meal in Period 1 followed by ABBV-7828 in fasting conditions in Period 2. |
| Name | Type | Description |
|---|---|---|
| ABBV-7828 | DRUG | Oral administration |
| Placebo for ABBV-7828 | DRUG | Oral administration |
Inclusion Criteria: * Individuals between 18 to 65 years of age at the time of screening. * BMI is \<= 18.0 to \>= 32.0 kg/m2. * A condition of general good health, based upon the results of a medical history, physical evaluations, vital signs, laboratory profile and a 12-lead ECG. Exclusion Crite...