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APG-2449

Phase 1

Advanced Solid Cancer | Small molecule | Oncology |Ascentage Pharma Group International - American Depository Shares|Last Updated: Jun 18, 2025

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment165
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT03917043APG-2449 in Patients With Advanced Solid TumorsPHASE1 RECRUITING 165May 27, 2019Jan 1, 2028Jun 18, 20259 China, China +7
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Study Design & Arms
AllocationNA
MaskingNONE
PurposeTREATMENT
Interventions
NameTypeDescription
APG-2449DRUGCapsule, multiple dose cohorts, oral administration every day (QD) of a 28-day cycle
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Recent Changes (Last 90 Days)
LOWMay 24, 2026NCT03917043studyFirstPostDate: changed