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Spyre Therapeutics Announces Grants of Inducement Awards - March 6, 2026

Key Takeaway: Spyre Therapeutics has announced the grant of stock options to two non-executive employees as part of its 2018 Equity Inducement Plan. The options, totaling 46,600 shares, are intended to incentivize new hires and are set to vest over time. This move aligns with Spyre's strategy to enhance its workforce while focusing on long-acting antibodies for inflammatory bowel disease and rheumatic diseases.

Market Sentiment Analysis

POSITIVE FACTORS

  • Spyre Therapeutics is expanding its team with new hires.
  • The stock options are part of a strategic plan to attract talent.
  • The company's focus on innovative treatments for IBD and rheumatic diseases shows promise.

Full Press Release Details

WALTHAM, Mass., March 06, 2026 (GLOBE NEWSWIRE) -- Spyre Therapeutics, Inc. (NASDAQ: SYRE) (the “Company” or “Spyre”), a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease and rheumatic diseases, today announced that Spyre’s independent Compensation Committee of the Board of Directors approved the grant of stock options to purchase an aggregate of 46,600 shares of common stock of Spyre to two non-executive employees as equity inducement awards under the Spyre Therapeutics, Inc. 2018 Equity Inducement Plan, as amended (the “2018 Plan”). The stock options were approved on March 2, 2026 and were material to each employee's acceptance of employment with Spyre, in accordance with Nasdaq Listing Rule 5635(c)(4).
The stock options were granted with a 10-year term and an exercise price equal to $42.49, the closing price per share of Spyre's common stock as reported by Nasdaq on March 2, 2026. The options granted to the employees shall vest and become exercisable as to one-fourth (1/4th) of the shares subject to the respective options on the first anniversary of the employee’s start date, and one-forty-eighth (1/48th) of the shares subject to the respective options shall vest and become exercisable monthly thereafter, in each case, subject to continuous service with Spyre through the applicable vesting dates. The stock options are subject to the terms of the 2018 Plan.

About Spyre Therapeutics

Spyre Therapeutics is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, and IL-23.
For more information, please visit http://spyre.com.

For Investors:Eric McIntyreSVP of Finance and Investor RelationsSpyre TherapeuticsEric.mcintyre@spyre.com

Frequently Asked Questions

What are the inducement awards granted by Spyre?

Spyre Therapeutics granted stock options to purchase 46,600 shares to two non-executive employees.

What is the exercise price for the stock options?

The exercise price for the stock options is $42.49 per share.

How will the stock options vest?

The options will vest 1/4th on the first anniversary and monthly thereafter.

What is the purpose of these inducement awards?

The awards are intended to incentivize new hires and attract talent to Spyre.

Last updated: Mar 9, 2026