Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT03415269 | A Study of the Effect of 20 mg Ambroxol Hydrochloride on Acute Cough. | PHASE2 | COMPLETED | 14 | — | — | Feb 15, 2018 | Apr 19, 2018 | Jun 20, 2019 | 1 | United Kingdom |
To assess the effect of single dose of 20 mg ambroxol lozenge on cough reflex sensitivity (quatified by recording the concenteration of cough stimulant evoking 2 (C2) and 5 (C5 ) coughs) to four different types of challenge agents in acute cough associated with URTI.
| Arm | Type | Description |
|---|---|---|
| 20 mg ambroxol | EXPERIMENTAL | 20 mg ambroxol lozenge delivered once on one day |
| Name | Type | Description |
|---|---|---|
| Ambroxol Hydrochloride | DRUG | single lozenge of 20mg ambroxol |
Inclusion Criteria: 1. Be informed of the nature of the study and have provided written informed voluntary consent; 2. Be able to speak, read, and understand English; 3. Be males or females, of any race, between 18 and 80 years of age, inclusive; 4. Subject has an acute cough and other symptoms con...