Recent Updates
Recently added Catalysts

REGN7041

Phase 1

Active Noninfectious Uveitis Affecting the Posterior Segment | Small molecule | Ophthalmology |Regeneron Pharmaceuticals, Inc.|Last Updated: Apr 22, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
CONTROLLEDBiomarker
Total Trials1
Total Enrollment72
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT07218770A Study of REGN7041 for Active Noninfectious Uveitis in Adult ParticipantsPHASE1 ACTIVE NOT_RECRUITING 72Dec 17, 2025Jun 28, 2028Apr 22, 20265 United States
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Occurrence of Treatment-Emergent Adverse Events (TEAEs)
Through Week 24
Secondary Endpoints
Concentrations of REGN7041 in serum
Through Week 24
Incidence of Anti-Drug Antibodies (ADAs) to REGN7041 in serum
Through Week 24
Magnitude of ADAs to REGN7041 in serum
Through Week 24
Unlock Study Endpoints
Study Design & Arms
AllocationNON_RANDOMIZED
MaskingNONE
ModelSEQUENTIAL
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Sequential Single Ascending Dose CohortsEXPERIMENTAL -
Sequential Multiple Ascending Dose CohortsEXPERIMENTAL -
Interventions
NameTypeDescription
REGN7041DRUGAdministered as per the protocol
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites5

Key Inclusion Criteria: 1. Diagnosis of non-infectious anterior, intermediate, posterior or panuveitis (For anterior uveitis, there must be evidence of inflammation affecting the posterior segment), as defined in the protocol 2. Active disease at baseline, as defined in the protocol 3. Part A only:...

Countries:United States
Unlock Eligibility Criteria
Recent Changes (Last 90 Days)
MEDIUMMay 26, 2026NCT07218770Status: RECRUITING → ACTIVE_NOT_RECRUITING
LOWMay 24, 2026NCT07218770studyFirstPostDate: changed