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NovoTTF-200T System

Phase 1

Adenocarcinoma of Lung | Unknown | Oncology |NovoCure Limited|Last Updated: Apr 9, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment25
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT05764954A Study of Tumor-Treating Fields (TTFields) in People With Lung AdenocarcinomaPHASE1 RECRUITING 25Aug 4, 2023Aug 1, 2027Apr 9, 20267 United States
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Study Endpoints
Primary Endpoints
Adverse events, severity and frequency
1 year

based on Common Terminology Criteria for Adverse Events (CTCAE) version 5.0

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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
NovoTTF-200T System Tumor-Treating Fields (TTFields)EXPERIMENTALFollowing pathological confirmation on of lung ADC, patients will proceed with TTFields treatment. The NovoTTF-200T System is an investigational medical device delivering 150 kHz TTFields to the patient's chest. The device is applied continuously for an average duration of 18 hours per day for 3 weeks (+/- 1 week).
Interventions
NameTypeDescription
NovoTTF-200T SystemDEVICEThe device is applied continuously for an average duration of 18 hours per day for 3 weeks (+/- 1 week).
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Eligibility Criteria
Age Range22 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites7

Inclusion Criteria: * The participant (or legally acceptable representative \[LAR\], if applicable) provides written informed consent for the study. * The participant is ≥22 years of age on the day of signing informed consent. * The participant has clinical stage 1A2, 1A3 or IB biopsy-proven lung A...

Countries:United States
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Recent Changes (Last 90 Days)
LOWMay 24, 2026NCT05764954studyFirstPostDate: changed