Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01021462 | A Study to Evaluate the Use of a Graded Infusion of Intravenous Glucose in the Assessment of Insulin Secretion Rates (MK-0000-078) | PHASE1 | COMPLETED | 12 | — | — | Aug 1, 2007 | Sep 1, 2007 | Jul 30, 2015 | - | — |
| Arm | Type | Description |
|---|---|---|
| Period 1 + Period 2 | EXPERIMENTAL | graded infusion of intravenous glucose |
| Name | Type | Description |
|---|---|---|
| Comparator: graded infusion of intravenous glucose | PROCEDURE | A stepwise graded infusion of glucose (20% dextrose \[D20\]) with a stable rate of infusion maintained for 40 minutes for each of 5 steps, with steps at 2,4,6,8 and 12mg/kg/min. Procedure will be identical in Period 1 and Period 2. |
Inclusion Criteria: * Subject is in good health * Subject is a non-smoker Exclusion Criteria: * Subject has a history of hypertension requiring treatment * Subject has a history of cancer * Subject's parents of siblings have a history of type 2 diabetes * Subject is unable to refrain from the use...